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Z-L-Pro-OtBu

Z-L-Pro-OtBu is a protected amino acid derivative consisting of L-proline bearing an N-Cbz (benzyloxycarbonyl, "Z") protecting group on the amino functionality and a tert-butyl ester ("OtBu") on the carboxyl group. The pyrrolidine side chain is incorporated as part of the proline scaffold, while the molecule contains the masked amine and masked carboxyl groups that reduce undesired side reactions during peptide coupling chemistry. Z-L-Pro-OtBu is used as a stepwise building block for peptide synthesis and related preparation of proline-containing peptide intermediates, where orthogonal protection and carboxyl ester masking support controlled formation of amide bonds.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25445

CAS No:16881-39-3

Synonyms/Alias:16881-39-3;Z-L-Pro-OtBu;Z-Pro-OtBu;N-Carbobenzoxy-L-prolinetert-ButylEster;(S)-1-Benzyl2-tert-butylpyrrolidine-1,2-dicarboxylate;ST51007312;ZINC02560788;Z-Pro-O-(tert-Butyl)-OH;SCHEMBL7318246;CTK8B3809;MolPort-006-122-036;OULMZZGGALAOLR-AWEZNQCLSA-N;N-Cbz-L-prolinetert-ButylEster;ZINC2560788;7540AH;ANW-43226;AKOS015891306;VZ33217;AJ-40650;AK-63176;Benzyloxycarbonyl-L-prolinetert.butylester;TR-007349;benzyloxy-carbonyl-L-prolinetert.butylester;C1764;FT-0637452

Chemical Name:N-alpha-Benzyloxycarbonyl-L-proline t-butyl ester

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M.F/Formula
C17H23NO4
M.W/Mr.
305,37 g/mole
Size
5 g;25 g;
InChI
1S/C17H23NO4/c1-17(2,3)22-15(19)14-10-7-11-18(14)16(20)21-12-13-8-5-4-6-9-13/h4-6,8-9,14H,7,10-12H2,1-3H3/t14-/m0/s1
InChI Key
OULMZZGGALAOLR-AWEZNQCLSA-N
Canonical SMILES
CC(C)(C)OC(=O)C1CCCN1C(=O)OCC2=CC=CC=C2

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