Z-L-Proline

Z-L-Proline contains the L-proline amino acid framework bearing a benzyloxycarbonyl (Cbz, Z) protecting group on the amino functionality, with a pyrrolidine ring that contributes a secondary amine-free side-chain and a carboxyl group available for acylation chemistry. The molecule features a Cbz carbamate that masks the α-amino group while retaining the carboxylic acid for coupling, and the stereochemistry is specified as L at the α-carbon. Z-L-Proline is used as a protected amino acid building block in peptide synthesis and related amide-bond formation workflows, where selective deprotection and controlled chemoselectivity support stepwise assembly of peptide derivatives.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01714

CAS No:1148-11-4

Synonyms/Alias:N-Benzyloxycarbonyl-L-proline;Z-Pro-OH;1148-11-4;N-CBZ-L-PROLINE;N-Carbobenzoxy-L-proline;Benzyloxycarbonyl-L-proline;Carbobenzyloxy-L-proline;N-Carbobenzyloxy-l-Proline;Carbobenzoxy-L-proline;Benzyloxycarbonylproline;Carbobenzoxy-S-proline;N-Benzyloxycarbonylproline;Z-L-Proline;1-(Benzyloxycarbonyl)proline;(S)-1-((Benzyloxy)carbonyl)pyrrolidine-2-carboxylicacid;(S)-N-CBZ-pyrrolidine-2-carboxylicacid;Carbobenzoxyproline;CBZ-L-PROLINE;CBZ-PRO-OH;1-Carbobenzoxy-L-proline;N-CBZ-L-PROLINE-OH;L-Proline,N-CBZprotected;(S)-1-(benzyloxycarbonyl)pyrrolidine-2-carboxylicacid;1-[(BENZYLOXY)CARBONYL]-L-PROLINE;N-(Benzyloxycarbonyl)-L-proline

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M.F/Formula
C13H15NO4
M.W/Mr.
249.3
Abbr
Z-Pro-OH
InChI
1S/C13H15NO4/c15-12(16)11-7-4-8-14(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,15,16)/t11-/m0/s1
InChI Key
JXGVXCZADZNAMJ-NSHDSACASA-N
Canonical SMILES
C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)O

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