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Z-L-Pyr-ONp

Z-L-Pyr-ONp is a protected amino acid derivative in which an L-configured pyrrolidine-containing amino acid (pyrrolinyl/pyrrolidine-type side chain) is converted to an ONp active ester, with the N-terminus masked by a benzyloxycarbonyl (Z, Cbz) protecting group. The molecule bears a carboxyl group activated as the p-nitrophenyl (ONp) ester for acyl transfer, while the amine functionality is protected as a carbamate and the side chain provides a cyclic secondary amine environment. Z-L-Pyr-ONp is used as an acylating building block in peptide synthesis and related amide-bond formation workflows, and it also serves as a reagent for preparing amino acid-containing conjugates and analytical standards where controlled acylation is required.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25834

CAS No:40356-52-3

Synonyms/Alias:Z-Pyr-ONp;40356-52-3;(S)-1-Benzyl2-(4-nitrophenyl)5-oxopyrrolidine-1,2-dicarboxylate;AmbotzZAA1245;AC1OLQXW;SCHEMBL9074152;MolPort-008-269-461;C19H16N2O7;ZINC4899535;AKOS016001540;DS-2196;AK-81339;Z-L-Pyroglutamicacid4-nitrophenylester;ST24026494;Z4707;M-9120;1-O-benzyl2-O-(4-nitrophenyl)(2S)-5-oxopyrrolidine-1,2-dicarboxylate;(2S)-5-Oxo-1,2-pyrrolidinedicarboxylicacid2-(4-nitrophenyl)1-benzylester

Chemical Name:(S)-N-alpha-Benzyloxycarbonyl-pyroglutamic acid p-nitrophenyl ester

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M.F/Formula
C19H16N2O7
M.W/Mr.
384,33 g/mole
Size
5 g;25 g;
InChI
1S/C19H16N2O7/c22-17-11-10-16(18(23)28-15-8-6-14(7-9-15)21(25)26)20(17)19(24)27-12-13-4-2-1-3-5-13/h1-9,16H,10-12H2/t16-/m0/s1
InChI Key
ZRQOXQJWPSHSDJ-INIZCTEOSA-N
Canonical SMILES
C1CC(=O)N(C1C(=O)OC2=CC=C(C=C2)[N+](=O)[O-])C(=O)OCC3=CC=CC=C3

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