Z-Leu-Arg-7-Amino-4-Methylcoumarin links a protected dipeptide to a fluorogenic AMC reporter, enabling sensitive protease-detection assays. Leucine and arginine define hydrophobic and basic recognition features. Researchers analyze cleavage kinetics via fluorescence output. Uses include substrate profiling, enzyme screening, and mechanistic studies.
CAT No: R2479
CAS No:156192-32-4
Synonyms/Alias:156192-32-4;Z-Leu-Arg-7-Amino-4-Methylcoumarin;Z-Leu-Arg-AMC;benzyl N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate;Z-Leu-Arg-Amc HCl;CBZ-Leu-Arg-AMC;CHEMBL126324;SCHEMBL5523268;BDBM12033;Cathepsin K Substrate (fluorogenic);MFCD07780911;FL110604;HY-142021;benzyloxycarbonyl-Leu-Arg-7-amino-4-methyl-coumarin;Benzyl ((S)-1-(((S)-5-guanidino-1-((4-methyl-2-oxo-2H-chromen-7-yl)amino)-1-oxopentan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)carbamate;benzyl (S)-1-((S)-5-guanidino-1-(4-methyl-2-oxo-2H-chromen-7-ylamino)-1-oxopentan-2-ylamino)-4-methyl-1-oxopentan-2-ylcarbamate;benzyl N-[(1S)-1-{[(1S)-4-carbamimidamido-1-[(4-methyl-2-oxo-2H-chromen-7-yl)carbamoyl]butyl]carbamoyl}-3-methylbutyl]carbamate;benzyl N-[(1S)-1-{[(1S)-4-carbamimidamido-1-[(4-methyl-2-oxochromen-7-yl)carbamoyl]butyl]carbamoyl}-3-methylbutyl]carbamate;
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