Z-Lys(Boc)-OMe is a protected lysine derivative in which the ε-amino group is protected as a Boc carbamate, the α-amino functionality is protected as a benzyloxycarbonyl (Z/Cbz-type) group, and the α-carboxyl group is converted to a methyl ester (OMe). The molecule therefore contains two protected nitrogen functionalities and a methyl ester carbonyl, with the side chain retaining the (protected) lysine backbone topology and a terminally Boc-protected ε-amino group suitable for chemoselective transformations during peptide assembly. In synthesis, it is employed as a stepwise amino acid building block for preparing peptide intermediates and protected peptide fragments, where the orthogonal protection pattern helps control side reactions while the ester and carbamate groups can be manipulated to match the requirements of subsequent coupling and deprotection steps.
CAT No: CP26845
CAS No:2389-49-3
Synonyms/Alias:Z-LYS(BOC)-OME;2389-49-3;SCHEMBL13430768;CTK4F2502;MolPort-006-114-261;ACT09380;ZINC5353598;METHYL6-N-BOC-2-N-CBZ-L-LYSINATE;FT-0698070;V4597;K-6468;L-Lysine,N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(phenylmethoxy)carbonyl]-,methylester;(S)-methyl13,13-dimethyl-3,11-dioxo-1-phenyl-2,12-dioxa-4,10-diazatetradecane-5-carboxylate
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