Z-N-Me-DL-Ala-OH · DCHA is a protected amino acid derivative of alanine in which the amino functionality is carbamate-protected with a benzyloxycarbonyl (Z/Cbz-like) group and additionally N-methylated, with the stereochemical descriptor "DL" indicating a racemic mixture at the alpha carbon and a free carboxylic acid present. The molecule contains a carboxyl group (-COOH) for acid-base behavior and peptide-coupling chemistry, while the Z-type protecting group and N-methyl substitution alter hydrogen-bonding and chemoselectivity by reducing the availability of the amino hydrogen. Presented as a DCHA salt, it is used as a defined alanine building block for controlled incorporation into peptide synthesis workflows and for preparing N-methylated alanine-containing peptide fragments or analogues in chemical biology and structure-activity studies.
1. TMEM16F and dynamins control expansive plasma membrane reservoirs
5. The spatiotemporal control of signalling and trafficking of the GLP-1R
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