Z-N-Me-Glu(OtBu)-OH

Name: Z-N-Me-Glu(OtBu)-OH
Brand: Creative Peptides
Rating: 5 (1 reviews)

Z-N-Me-Glu(OtBu)-OH is a protected, N-methylated glutamic acid derivative bearing a Z (benzyloxycarbonyl) group on the amino functionality and a tert-butyl ester on the side-chain carboxyl group, with the α-carboxylic acid present as a free carboxylic acid (-CO2H). The molecule contains an N-methyl substituent that modifies the amide-forming nitrogen reactivity, while the Z carbamate and OtBu ester protect the corresponding functional groups from undesired side reactions during peptide coupling chemistry. Z-N-Me-Glu(OtBu)-OH is used as a stepwise building block in peptide synthesis and related amino acid derivatization workflows, where orthogonal protection enables controlled handling of the α-amino and carboxyl functionalities while the side-chain carboxyl remains masked as an ester.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27108

CAS No:42417-71-0

Synonyms/Alias:42417-71-0;Z-N-Me-Glu(OtBu)-OH;(S)-2-(((Benzyloxy)carbonyl)(methyl)amino)-5-(tert-butoxy)-5-oxopentanoicacid;AmbotzZAA1013;MolPort-008-269-404;ZINC2560786;AKOS016002131;AJ-40648;AK-49790;ST24035802;Z5871;K-8811;L-Glutamicacid,N-methyl-N-[(phenylmethoxy)carbonyl]-,5-(1,1-dimethylethyl)ester

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C18H25NO6

M.W/Mr.

351.4

Size

1 g;5 g;

InChI

1S/C18H25NO6/c1-18(2,3)25-15(20)11-10-14(16(21)22)19(4)17(23)24-12-13-8-6-5-7-9-13/h5-9,14H,10-12H2,1-4H3,(H,21,22)/t14-/m0/s1

InChI Key

XPZXECGLTZKQDX-AWEZNQCLSA-N

Canonical SMILES

CC(C)(C)OC(=O)CCC(C(=O)O)N(C)C(=O)OCC1=CC=CC=C1

1. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

2. TMEM16F and dynamins control expansive plasma membrane reservoirs

3. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

4. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

5. Tachykinin-related peptides modulate immune-gene expression in the mealworm beetle Tenebrio molitor L

Useful Tools

Peptide Calculator

Abbreviation List

Peptide Glossary

If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.

Featured Services

Peptide Analysis Services Peptide CDMO Peptide Nucleic Acids Synthesis Peptide Synthesis Services Peptide Modification Services Epitope Mapping Services cGMP Peptide Service Custom Conjugation Service

Hot Products

Aviptadil Acetate

Aviptadil Acetate is a vasoactive intestinal peptide for lung and immune research. Purchase this synthetic peptide for studies on pulmonary health and inflammation.

Terlipressin

Terlipressin is a synthetic vasopressin analog that supports vascular and renal research. Purchase Terlipressin peptide from a verified supplier for liver and hemodynamic studies.

Fertirelin Acetate

Fertirelin Acetate is a synthetic peptide that promotes ovulation and fertility. Purchase Fertirelin research peptide for breeding and hormonal studies.

Thymopentin Acetate

Thymopentin Acetate peptide enhances immune modulation and T-cell function. Purchase Thymopentin research peptide online for immunotherapy and cell biology research.

Alarelin acetate

Alarelin Acetate is a high-purity synthetic peptide used in fertility and ovulation research. Buy Alarelin peptide online from a trusted peptide supplier for advanced hormonal studies.

Deslorelin

Deslorelin peptide is a potent GnRH agonist used for fertility and hormonal control. Buy Deslorelin peptide powder online for veterinary and endocrine research applications.

Argipressin

Argipressin peptide regulates water balance and blood pressure in biological systems. Shop pure Argipressin peptide online for cardiovascular and kidney research.

Antide

Antide is a GnRH antagonist peptide used in reproductive hormone research. Buy Antide peptide powder from a reliable peptide supplier for endocrine studies.

Lanreotide Acetate

Lanreotide Acetate is a somatostatin analog peptide regulating hormone secretion. Purchase Lanreotide peptide online to study tumor suppression and endocrine disorders.

Somatostatin

Somatostatin peptide inhibits the secretion of growth hormone and insulin. Purchase high-purity Somatostatin for metabolic, neuroendocrine, and cancer research.

About us

Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

Our Customers