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Z-N-Me-Nle-OH

Z-N-Me-Nle-OH is a protected, N-methylated amino acid derivative in which the side chain corresponds to norleucine (Nle), featuring a straight-chain aliphatic functionality and an N-methyl substitution on the amino nitrogen. The molecule contains a benzyloxycarbonyl (Z, Cbz) protecting group on the amino terminus, along with a free carboxylic acid (-COOH), and the N-methylation changes the amide-forming reactivity and conformational behavior relative to the corresponding unmodified norleucine. Z-N-Me-Nle-OH is used as a building block in peptide synthesis and related derivatization workflows where a protected, sterically and electronically modified amino acid residue is required for controlled coupling and incorporation into peptide or peptide-like structures.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26820

CAS No:225386-32-3

Synonyms/Alias:Z-N-ME-L-2-AMINOHEXANOICACID;225386-32-3;Z-N-methyl-L-norleucine;TMA045;MolPort-020-004-029;ZINC2392295;N-Methyl-N-(benzyloxycarbonyl)-L-norleucine;K-6319

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  • IND and NDA support
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M.F/Formula
C15H21NO4
M.W/Mr.
279.34
Size
1 g;5 g;
InChI
1S/C15H21NO4/c1-3-4-10-13(14(17)18)16(2)15(19)20-11-12-8-6-5-7-9-12/h5-9,13H,3-4,10-11H2,1-2H3,(H,17,18)/t13-/m0/s1
InChI Key
ZRIGUBDEWMLBRB-ZDUSSCGKSA-N
Canonical SMILES
CCCCC(C(=O)O)N(C)C(=O)OCC1=CC=CC=C1

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