Z-N-Me-Nle-OH is a protected, N-methylated amino acid derivative in which the side chain corresponds to norleucine (Nle), featuring a straight-chain aliphatic functionality and an N-methyl substitution on the amino nitrogen. The molecule contains a benzyloxycarbonyl (Z, Cbz) protecting group on the amino terminus, along with a free carboxylic acid (-COOH), and the N-methylation changes the amide-forming reactivity and conformational behavior relative to the corresponding unmodified norleucine. Z-N-Me-Nle-OH is used as a building block in peptide synthesis and related derivatization workflows where a protected, sterically and electronically modified amino acid residue is required for controlled coupling and incorporation into peptide or peptide-like structures.
CAT No: CP26820
CAS No:225386-32-3
Synonyms/Alias:Z-N-ME-L-2-AMINOHEXANOICACID;225386-32-3;Z-N-methyl-L-norleucine;TMA045;MolPort-020-004-029;ZINC2392295;N-Methyl-N-(benzyloxycarbonyl)-L-norleucine;K-6319
1. High fat diet and GLP-1 drugs induce pancreatic injury in mice
5. TMEM16F and dynamins control expansive plasma membrane reservoirs
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.