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Z-N-α-Methyl-L-valine

Z-N-α-Methyl-L-valine is a protected, non-natural valine derivative in which the α-methyl group modifies the amino acid backbone and the N-terminus is protected as a Z (benzyloxycarbonyl, Cbz) carbamate. The molecule contains an α-amino nitrogen and a carboxyl functional group, with the stereochemistry indicated as L for the valine-derived center while the N-protection and α-methyl substitution influence conformational preferences and side-chain accessibility (isopropyl group) during coupling chemistry. Z-N-α-Methyl-L-valine is used as a building block for peptide synthesis and structure-activity studies where incorporation of an α-methylated, Z-protected amino acid residue is used to modulate backbone sterics and peptide-like properties, including in solid-phase or solution-phase synthetic sequences.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP02235

CAS No:42417-65-2

Synonyms/Alias:Cbz-N-methyl-L-valine;42417-65-2;Z-N-Me-Val-OH;Cbz-N-Me-Val-OH;Z-N-methyl-L-valine;AmbotzZAA1019;Cbz-N-D-Me-Val-OH;AC1Q1NQQ;Cbz-N-Methyl-L-Val-OH;SCHEMBL1085849;Z-N-;00913_FLUKA;CTK8B9884;MolPort-003-925-120;NNEHOKZDWLJKHP-LBPRGKRZSA-N;ZINC2526289;ANW-63419;SBB064568;N-benzyloxycarbonyl-N-methyl-L-valine;AKOS015890054;VA50551;AJ-37589;AK-81335;SC-10013;TC-152164

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M.F/Formula
C14H19NO4
M.W/Mr.
265.3
Abbr
Z-MeVal-OH
InChI
1S/C14H19NO4/c1-10(2)12(13(16)17)15(3)14(18)19-9-11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3,(H,16,17)/t12-/m0/s1
InChI Key
NNEHOKZDWLJKHP-LBPRGKRZSA-N
Canonical SMILES
CC(C)C(C(=O)O)N(C)C(=O)OCC1=CC=CC=C1

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