Z-1-Nal-OH

Z-1-Nal-OH is a protected amino acid derivative featuring a 1-naphthylalanine (Nal) side chain, where the alpha-amino group is masked with a benzyloxycarbonyl (Z, Cbz) protecting group and the carboxyl group is present as a free acid (-COOH). The molecule therefore contains a Z-carbamate-protected amino functionality alongside an unprotected carboxylic acid, with the aromatic naphthyl side chain providing a hydrophobic, π-rich handle for incorporation into peptide-like structures. Z-1-Nal-OH is used as a building block in peptide synthesis and related structure-activity studies where stepwise coupling and controlled chemoselectivity are required for introducing a Nal residue into protected or partially protected amino acid sequences.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27327

CAS No:65365-15-3

Synonyms/Alias:Cbz-3-(1-naphthyl)-L-Ala;65365-15-3;Z-1-Nal-OH;SCHEMBL7444765;HNYQEAGTPQSPLT-IBGZPJMESA-N;ZINC2561176;6523AH;FT-0641013;N-benzyloxycarbonyl-3-(1-naphthyl)-L-alanine;(2S)-2-{[(benzyloxy)carbonyl]amino}-3-naphthalen-1-ylpropanoicacid

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M.F/Formula
C21H19NO4
M.W/Mr.
349.39
Size
1 g;5 g;
InChI
1S/C21H19NO4/c23-20(24)19(22-21(25)26-14-15-7-2-1-3-8-15)13-17-11-6-10-16-9-4-5-12-18(16)17/h1-12,19H,13-14H2,(H,22,25)(H,23,24)/t19-/m0/s1
InChI Key
HNYQEAGTPQSPLT-IBGZPJMESA-N
Canonical SMILES
C1=CC=C(C=C1)COC(=O)NC(CC2=CC=CC3=CC=CC=C32)C(=O)O

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