Z-Nle-OSu is a protected amino acid derivative in which norleucine (Nle) is converted to an N-hydroxysuccinimide (OSu) ester and the amino group is protected with a benzyloxycarbonyl (Z, Cbz-type) group. The molecule bears a Z-carbamate on nitrogen and an activated carboxylate as the OSu ester, providing an electrophilic acyl-transfer handle while maintaining chemoselectivity relative to the unprotected carboxylic acid. Z-Nle-OSu is used as an activated amino acid building block for peptide coupling and amide-bond formation in solution-phase or solid-phase synthesis, and it can also function as a reagent for preparing amino-acid-derived conjugates where controlled acylation is required.
CAT No: CP27062
CAS No:36360-62-0
Synonyms/Alias:Z-L-2-aminohexanoic acid-N-hydroxysuccinimide ester
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