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Z-O-tert.butyl-D-tyrosine dicyclohexylamine salt

Z-O-tert.butyl-D-tyrosine dicyclohexylamine salt is a protected tyrosine derivative in which the phenolic hydroxyl of the D-tyrosine side chain is masked as a tert-butyl ether (O-tert-butyl) and the α-amino group is protected with a benzyloxycarbonyl-type Z (Cbz) group, yielding a zwitterionic amino acid framework paired as a dicyclohexylamine salt. The molecule contains a Z-protected amino functionality and a free carboxylic acid (or its salt-associated form), while the aromatic phenyl ring bears the tert-butyl-protected phenoxy substituent that modulates polarity and suppresses phenol reactivity during peptide coupling. As a protected amino acid salt, it is used in stepwise peptide synthesis and related derivatization workflows where controlled chemoselectivity for the carboxyl/activated amino functionality is required, and the phenolic protection supports incorporation of tyrosine residues into peptide analogues or further chemical studies of aromatic side-chain behavior.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP02127

CAS No:198828-72-7

Synonyms/Alias:198828-72-7;Z-D-Tyr(tBu)-OHDCHA;z-d-tyr(tbu)-oh.dcha;Dicyclohexylamine(R)-2-(((benzyloxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoate;C33H48N2O5;Z-D-Tyr(tBu)-OHCHA;Z-D-Tyr(But)-OHdcha;MolPort-016-580-316;0217AB;CZ-133;AKOS015910989;VA50021;AK-81322;ST24046496;K-5816;I14-39006;Z-D-Tyr(tBu)-OHinvertedexclamationmarkcurrencyDCHA;Z-O-tertinvertedexclamationmarkcurrencybutyl-D-tyrosinedicyclohexylaminesalt

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M.F/Formula
C33H48N2O5
M.W/Mr.
552.8
Abbr
Z-D-Tyr(tBu)-OH.DCHA
InChI
1S/C21H25NO5.C12H23N/c1-21(2,3)27-17-11-9-15(10-12-17)13-18(19(23)24)22-20(25)26-14-16-7-5-4-6-8-16;1-3-7-11(8-4-1)13-12-9-5-2-6-10-12/h4-12,18H,13-14H2,1-3H3,(H,22,25)(H,23,24);11-13H,1-10H2/t18-;/m1./s1
InChI Key
FDNJRKLIHBJXIR-GMUIIQOCSA-N
Canonical SMILES
CC(C)(C)OC1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2.C1CCC(CC1)NC2CCCCC2

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