Z-Pro-betaNA

Z-Pro-betaNA contains a proline residue bearing an N-benzyloxycarbonyl (Z, Cbz-type) protecting group on the amino nitrogen and a betaNA (beta-naphthylamide) functional group attached to the corresponding carboxyl-derived moiety, forming a derivatized amino acid/amide intermediate rather than a free amino acid. The molecule retains the proline ring's secondary amine within the cyclic backbone while the side chain is constrained by the pyrrolidine framework, and the Z group provides a carbamate-type protection that suppresses undesired amide/peptide coupling at the amino functionality during stepwise synthesis. Z-Pro-betaNA is used as a substrate-like building block in peptide chemistry and analytical assays where a proline-containing, chromogenic or fluorogenic beta-naphthylamide handle can be monitored during enzymatic or chemical transformations.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27547

CAS No:86925-99-7

Synonyms/Alias:Z-L-prolinebeta-naphthylamide;86925-99-7;SCHEMBL4613461;CTK8G3868;ZINC641408

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M.F/Formula
C23H22N2O3
M.W/Mr.
374.44
Size
1 g;5 g;
InChI
1S/C23H22N2O3/c26-22(24-20-13-12-18-9-4-5-10-19(18)15-20)21-11-6-14-25(21)23(27)28-16-17-7-2-1-3-8-17/h1-5,7-10,12-13,15,21H,6,11,14,16H2,(H,24,26)/t21-/m0/s1
InChI Key
JNQYOPCQZVPOCL-NRFANRHFSA-N
Canonical SMILES
C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)NC3=CC4=CC=CC=C4C=C3

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