Z-Tyr-NH2 is a protected tyrosine amino acid derivative in which the tyrosine side chain bears a phenolic hydroxyl while the alpha-amino group is present as a free primary amine (-NH2) and the alpha-carboxyl group is converted to a C-terminal Z (benzyloxycarbonyl, Cbz) carbamate protecting group. The molecule therefore contains a phenolic -OH on the aromatic ring, an unprotected primary amine at the alpha position, and a benzyloxycarbonyl-protected carboxyl functionality that modulates chemoselectivity by masking the carboxylate and providing a stable protecting group during peptide-coupling steps. Z-Tyr-NH2 is used as a building block for preparing tyrosine-containing peptides and peptide-related intermediates, where the protected carboxyl component supports controlled assembly of amide bonds while the phenolic hydroxyl can serve as a handle for subsequent derivatization or selective protection strategies.
CAT No: CP26618
CAS No:19898-39-6
Synonyms/Alias:Z-TYR-NH2;CHEMBL65770;19898-39-6;MolPort-020-004-742;ZINC1576081;7972AH;BDBM50043817;CJ-24881;K-5820;[(S)-1-Carbamoyl-2-(4-hydroxy-phenyl)-ethyl]-carbamicacidbenzylester
1. An Open-label, Single-center, Safety and Efficacy Study of Eyelash Polygrowth Factor Serum
3. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
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