Z-Tyr(tBu)-OMe

Z-Tyr(tBu)-OMe is a protected tyrosine derivative in which the phenolic side chain bears a tert-butyl substituent and the carboxyl group is present as a methyl ester (OMe), while the amino functionality is protected by a benzyloxycarbonyl (Z) group. The molecule contains a substituted aromatic ring with a tert-butyl-protected phenol, along with an N-protected amino group and an esterified carboxyl group, which together modulate polarity and chemoselectivity during peptide-building steps. Z-Tyr(tBu)-OMe is used as a stepwise amino acid building block for preparing peptide and peptidomimetic structures, including workflows that require temporary masking of the phenolic hydroxyl and controlled handling of the amino and carboxyl functionalities.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27157

CAS No:5068-29-1

Synonyms/Alias:Z-TYR(TBU)-OME;5068-29-1;L-Tyrosine,O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-,methylester;Z-TYR-OME;SCHEMBL13919532;MolPort-020-004-704;ZINC2560793;7971AH;AKOS015913833;AK170103;K-9368;N-(Benzyloxycarbonyl)-O-tert-butyl-L-tyrosinemethylester

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M.F/Formula
C22H27NO5
M.W/Mr.
385.46
Size
5 g;25 g;
InChI
1S/C22H27NO5/c1-22(2,3)28-18-12-10-16(11-13-18)14-19(20(24)26-4)23-21(25)27-15-17-8-6-5-7-9-17/h5-13,19H,14-15H2,1-4H3,(H,23,25)/t19-/m0/s1
InChI Key
IPRNNTJYTNRIDM-IBGZPJMESA-N
Canonical SMILES
CC(C)(C)OC1=CC=C(C=C1)CC(C(=O)OC)NC(=O)OCC2=CC=CC=C2

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