Introduction GsMTx4 is a synthetic and biologically active peptide toxin. Its molecular formula is C185H273N49O45S6, with the chemical structure of Gly-Cys-Leu-Glu-Phe-Trp-Trp-Lys-Cys-Asn-Pro-Asn-Asp-

Introduction ICI 174,864 is an opioid peptide, belonging to subclasses of opioid receptors. Its chemical structure is N, N-diallyl-Tyr-Aib-Aib-Phe-Leu. It has significant effects in various kinds of c

Introduction  st-Ht31, a protein kinase A (PKA)-anchoring inhibitor, greatly induces robust cholesterol or phospholipid efflux from macrophage foam cells, providing an effective treatment against ath

Introduction PM102 is a novel synthetic peptide that effectively reverses the anticoagulant effect of heparin. It can be used as a bolus and infusion, and its rapid efficacy and rapid clearance make i

Introduction Phosphoramidon is a kind of thermolysin inhibitor isolated from a culture filtrate of streptomyces. It has proved that phosphoramidon can inhibit endothelin converting enzyme and inhibit

Introduction MEN 11270 (H-DArg-Arg-Pro-Hyp-Gly-Thi-c(Dab-Dtic-Oic-Arg)c(7γ-10α)) is a novel selective constrained peptide antagonist, with potency and selectivity comparable to those of the linear pep

Introduction Long-term potentiation (LTP) is a persistent synaptic enhancement which is thought to be a substrate for memory. It has been proved that the constitutively active form of an atypical prot

Introduction The cyclopentapeptide FC 131 (cyclo(-L-Arg1-L-Arg2-L-2-Nal3-Gly4-D-Tyr5-), 2-Nal=3-(2-naphthyl) alanine)) is an antagonist for CXC-chemokine receptor 4 (CXCR4), which plays a role in HIV-

Introduction MSG 606 (Cyclo-[(CH2) 3CO-Gly-His-D-Phe-Arg-D-Trp-Cys(S-)]-Asp-Arg-Phe-Gly-NH2) is a potent and novel cyclic thioether peptide, and selectively antagonizes the MC1R (melanocyte stimulatin

Introduction BIO 1211, is a non-covalent, small-molecule, cyclohexanecarboxylic acid base compound, tight-binding inhibitor (Koff =1.4×10-4 s-1, dissociation constant [Kd]= 70 pM) of VLA-4 (Very Late

Introduction The toxin BeKm 1 is a HERG-specific peptide toxin, which are voltage-gated K+ channels, coded by the human ether-a-go-go-related gene. BeKm 1 was isolated from the venom of the Central As

Introduction Astressin 2B is a peptidic antagonist to CRF2 (corticotrophin-releasing factor 2) receptor with structure of cyclo (31-34) [DPhe11, His12, CαMeLeu13,39, Nle17, Glu31, Lys34] Ac-Sauvagine(

Introduction Aprotinin is a natural proteinase inhibitor polypeptide derived from bovine lung tissue. It is a monomeric globular polypeptide which consists of a chain of 58 amino acids (C284H432N84O

Introduction AdTx1, also called as ρ-Da1a, is a polypeptide of 65 amino acids stabilized by four disulfide bonds, which has a strong affinity for the G-protein-coupled α1A-adrenoceptor. Adrenoceptors

Introduction Acetyl pepstatin, nature products of yeast fermentation, is general inhibitors of the family of aspartic proteases with the structure of Ac-Val-Val-Sta-Ala-Sta-OH, where staine (Sta) is t

Introduction TC 14012 is a serum-stable derivative of the peptidomimetic T140, which is a cyclic peptide with the structure of [Cit6, D-Cit8]-T140 and contains the C-terminal amide. T140 is a typicall

Introduction Urantide is a UⅡ receptor antagonist. It can effectively alleviate monocrotaline (MCT)-induced PAH in a rat model, probably by relaxing pulmonary arteries and blocking pulmonary vascular

Introduction Norleual is a potent inhibitor of the HGF/Met system, which inhibited the prosurvival effects of HGF and suppressed lung colonization in a murine melanoma cell model. The activation step

Introduction NoxA1ds is derived from a peptide whose structure is based on a short sequence of an essential Nox subunit. It binds directly to NOX1 and displaces NOXA1 to inhibit enzymatic activity and

Introduction Tertiapin-Q (TPN-Q) is a small compact protein that contains twenty-one amino acids, which derived from bee venom toxin tertiapin (TPN), and it is obtained by replacing methionine residue

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 Somatostatin (SST) is a peptide compound synthesized by neuroendocrine cells and other cells that can label tumo ...

An overview of Tripeptide-10 Citrulline  Signal oligopeptides are commonly synthesized from portions of EMPs and from natural ...

  UFP-803 (H-Asp-c[Pen-Phe-DTrp-Dab-Tyr-Cys]-Val-OH), [Pen 5, DTrp 7, Dab 8] U-II (4-11), is a peptidic UT (urote ...

 Zonisamide, sold as brand name Zonegran, is a derivative of 3-(sulfamoylmethyl)-l,2-benzisoxazole. It is a membe ...

 BIO 1211, is a non-covalent, small-molecule, cyclohexanecarboxylic acid base compound, tight-binding inhibitor ( ...

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