10Panx is a mimetic inhibitory peptide of panx1, which blocks pannexin-1 gap junctions, inhibits p2x7-mediated dye uptake, atp-mediated il-1β release and caspase-1 activation, but does not alter membrane current in macrophages in vitro.
CAT# | R0961 |
CAS | 955091-53-9 |
M.F/Formula | C58H79N15O16 |
M.W/Mr. | 1242.37 |
Sequence | Trp-Arg-Gln-Ala-Ala-Phe-Val-Asp-Ser-Tyr |
Labeling Target | Gap Channels |
Purity | >98% |
Activity | Inhibitor |
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