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  5. [Ala1,3,11,15]-Endothelin 1

[Ala1,3,11,15]-Endothelin 1

This is a peptide that contains the amino acid sequence alanine at positions 1, 3, 11 and 15.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: 10-101-284

CAS No:121204-87-3

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C109H163N25O32S
M.W/Mr.
2367.67
Sequence
One Letter Code: ASASSLMDKEAVYFAHLDIIW
Three Letter Code: Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
Appearance
White or off-white lyophilized powder
Activity
Selective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
Long-term Storage Conditions
Soluble to 1 mg/ml in water
Shipping Condition
Room temperature
InChI Key
NRTWVLDGYXCWHD-IGKRDWOESA-N
Canonical SMILES
CCC(C)C(C(=O)NC(C(C)CC)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CC3=CNC=N3)NC(=O)C(C)NC(=O)C(CC4=CC=CC=C4)NC(=O)C(CC5=CC=C(C=C5)O)NC(=O)C(C(C)C)NC(=O)C(C)NC(=O)C(CCC(=O)O)NC(=O)C(CCCCN)NC(=O)C(CC(=O)O)NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CO)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(C)N

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