[Ala1,3,11,15]-Endothelin 1

Tetracosactide is a synthetic peptide, which corresponds to the first 24 amino acids of the naturally occurring hormone ACTH (adrenocorticotropic hormone). It stimulates the adrenal cortex to produce corticosteroids, mineralocorticoids, and, to a lesser extent, androgens.

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CAT#10-101-284
M.F/FormulaC109H163N25O32S
M.W/Mr.2367.67
SequenceOne Letter Code: ASASSLMDKEAVYFAHLDIIW
Three Letter Code: Ala-Ser-Ala-Ser-Ser-Leu-Met-Asp-Lys-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp
AppearanceWhite or off-white lyophilized powder
ActivitySelective ETB endothelin receptor agonist (IC50 values are 0.33 and 2200 nM for displacing [125I]-ET-1 from ETB and ETA receptors respectively).
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