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alpha-conotoxin ImI

α-Conotoxin ImI is a disulfide-rich, cysteine-constrained peptide from cone snail venom targeting nicotinic receptor subtypes in research settings. Its compact fold and defined loop architecture enable high-affinity binding. Researchers examine structure-activity relationships via NMR and mutagenesis. Applications include ion-channel mapping, neurotoxin motif analysis, and conformational-stability studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
alpha-conotoxin ImI(CAS 156467-85-5)

CAT No: PI-024

CAS No:156467-85-5

Synonyms/Alias:alpha-Conotoxin imi;alpha-Ctx-imi;156467-85-5;Gly-cys-cys-ser-asp-pro-arg-cys-ala-trp-arg-cys-NH2;DTXSID10166085;Glycyl-cysteinyl-cysteinyl-seryl-asparginyl-prolyl-arginyl-cysteinyl-alanyl-tryptophyl-arginyl-cysteinamide;L-Cysteinamide, glycyl-L-cysteinyl-L-cysteinyl-L-seryl-L-alpha-aspartyl-L-prolyl-L-arginyl-L-cysteinyl-L-alanyl-L-tryptophyl-L-arginyl-, cyclic (2-8),(3-12)-bis(disulfide);alpha-CTX IMI;CHEMBL500076;DTXCID7088576;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C52H82N20O15S4
M.W/Mr.
1355.6
Sequence
One Letter Code:GCCSDPRCAWRC
Three Letter Code:H-Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Ala-Trp-Arg-Cys-NH2
InChI
InChI=1S/C52H82N20O15S4/c1-24(41(78)66-30(15-25-18-61-27-8-3-2-7-26(25)27)44(81)64-28(9-4-12-59-51(55)56)42(79)69-33(20-88)40(54)77)62-46(83)35(22-90)70-43(80)29(10-5-13-60-52(57)58)65-49(86)37-11-6-14-72(37)50(87)31(16-39(75)76)67-45(82)32(19-73)68-48(85)36(23-91)71-47(84)34(21-89)63-38(74)17-53/h2-3,7-8,18,24,28-37,61,73,88-91H,4-6,9-17,19-23,53H2,1H3,(H2,54,77)(H,62,83)(H,63,74)(H,64,81)(H,65,86)(H,66,78)(H,67,82)(H,68,85)(H,69,79)(H,70,80)(H,71,84)(H,75,76)(H4,55,56,59)(H4,57,58,60)/t24-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-/m0/s1
InChI Key
IFMXNBRHEQLZMI-VAYQAVKTSA-N

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