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Angiotensinogen (1-14), Porcine

Angiotensinogen (1-14) is a fragement of full-length Angiotensinogen which can be hydrolyzed by Renin to form Angoiotensin I. Renin controls vasocontriction and blood pressure as part of the Renin-angiotensin system (RAS).

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1694

CAS No:20845-02-7

Synonyms/Alias:Hypertensinogen;20845-02-7;Angiotensinogen (1-14);Angiotensinogen (1-14) porcine;Porcine renin substrate tetradecapeptide;Angiotensinogen (tetradecapeptide renin substrate), 5-L-isoleucine-;DTXSID701346983;HY-P4774;NCGC00167226-01;CS-0656363;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
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M.F/Formula
C85H123N21O20
M.W/Mr.
1759
Sequence
One Letter Code:DRVYIHPFHLLVYS
Three Letter Code:H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH
Appearance
White powder
Purity
>97% (by HPLC)
Source#
Synthetic
Length
14
Shipping Condition
Shipped at room temperature
InChI
InChI=1S/C85H123N21O20/c1-11-48(10)70(105-78(119)62(35-51-23-27-55(109)28-24-51)100-80(121)68(46(6)7)103-72(113)57(19-15-29-91-85(87)88)94-71(112)56(86)38-67(110)111)82(123)101-64(37-53-40-90-43-93-53)83(124)106-30-16-20-66(106)79(120)98-60(33-49-17-13-12-14-18-49)74(115)97-63(36-52-39-89-42-92-52)76(117)95-58(31-44(2)3)73(114)96-59(32-45(4)5)77(118)104-69(47(8)9)81(122)99-61(34-50-21-25-54(108)26-22-50)75(116)102-65(41-107)84(125)126/h12-14,17-18,21-28,39-40,42-48,56-66,68-70,107-109H,11,15-16,19-20,29-38,41,86H2,1-10H3,(H,89,92)(H,90,93)(H,94,112)(H,95,117)(H,96,114)(H,97,115)(H,98,120)(H,99,122)(H,100,121)(H,101,123)(H,102,116)(H,103,113)(H,104,118)(H,105,119)(H,110,111)(H,125,126)(H4,87,88,91)/t48-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,68-,69-,70-/m0/s1
InChI Key
XJFQCYIFOWHHFN-PLKCGDGVSA-N
Canonical SMILES
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC4=CN=CN4)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(CC5=CC=C(C=C5)O)C(=O)NC(CO)C(=O)O)NC(=O)C(CC6=CC=C(C=C6)O)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)O)N

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