Annexin A1 (1-25) (dephosphorylated) (human)

Ac2-26 is Annexin A1 (AnxA1) N-terminal-derived peptide, and acts as inhibitor of leukocyte extravasation. It can reduce neutrophil adhesion and emigration, promote detachment of neutrophils from activated mesenteric endothelium and accelerate epithelial wound repair after induced colonic injury in mice in vivo. It shows anti-inflammatory effect.

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CAT#10-101-239
Chemical Structure
CAS151988-33-9
Synonyms/AliasAnnexin-1 (2-26) (human), Ac2-26, Lipocortin-1 (2-26), Calpactin II (1-25) (dephosphorylated) (human)
M.F/FormulaC141H210N32O44S
M.W/Mr.3089.43
SequenceOne Letter Code: Ac-AMVSEFLKQAWFIENEEQEYVQTVK
Three Letter Code: Ac-Ala-Met-Val-Ser-Glu-Phe-Leu-Lys-Gln-Ala-Trp-Phe-Ile-Glu-Asn-Glu-Glu-Gln-Glu-Tyr-Val-Gln-Thr-Val-Lys-OH
Labeling TargetCell Adhesion Molecules
AppearanceWhite lyophilised solid
Purity>98%
ActivityInhibitor
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