Bax inhibitor peptide V5

BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet, and anti-cancer drug.

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CAT#R1852
CAS579492-81-2
Synonyms/AliasBIP-V5
Chemical Name(S)-6-amino-2-((Z)-((S)-2-((Z)-((S)-2-((Z)-(((S)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-yl)(hydroxy)methylene)amino)-1-hydroxy-4-(methylthio)butylidene)amino)-1-hydroxy-4-methylpentylidene)amino)hexanoic acid
M.F/FormulaC27H50N6O6S
M.W/Mr.586.8
SequenceOne Letter Code: VPMLK
Three Letter Code: H-Val-Pro-Met-Leu-Lys-OH
Labeling TargetApoptosis
AppearanceCrystalline solid
Purity≥97% (HPLC)
ActivityInhibitor
Areas of InterestCancer
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