BQ-123 is a synthetic cyclic peptide used to investigate structural determinants within endothelin-receptor systems. Its defined loop topology supports binding, folding, and docking analyses. The sequence aids in mapping minimal motifs responsible for peptide-protein recognition. Applications include ligand modeling and structural biochemistry.
CAT No: E09057
CAS No:136553-81-6
Synonyms/Alias:BQ-123;136553-81-6;BQ123;Cyclo(D-trp-D-asp-pro-D-val-leu);BQ 123;cyclo(Trp-Asp-Pro-Val-Leu);UNII-S2A8YZM151;CHEBI:2965;CHEMBL314691;S2A8YZM151;2-[(3R,6R,9S,12R,15S)-6-(1H-indol-3-ylmethyl)-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazabicyclo[13.3.0]octadecan-3-yl]acetic acid;2-((3R,6S,9R,12R,17aS)-9-((1H-indol-3-yl)methyl)-6-isobutyl-3-isopropyl-1,4,7,10,13-pentaoxohexadecahydro-1H-pyrrolo[1,2-a][1,4,7,10,13]pentaazacyclopentadecin-12-yl)acetic acid;Cyclo(D-trp-D-asp-L-pro-D-val-L-leu);Cyclo[D-trp-D-asp-L-pro-D-val-L-leu];BQ-123 sodium salt;cyclo(D-Asp-Pro-D-Val-Leu-D-Trp);cyclo[D-Trp-D-Asp-Pro-D-Val-Leu];cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu);cyclo-(D-Asp-Pro-D-Val-Leu-D-Trp);cyclo-[D-Asp-Pro-d-Val-Leu-d-Trp];cyclo(D-Asp-L-Pro-D-Val-L-Leu-D-Trp);cyclo[(D)Trp-(D)Asp-Pro-(D)Val-Leu];cyclo[D-Asp-L-Pro-D-Val-L-Leu-D-Trp];C31H42N6O7;2-((3R,6R,9S,12R,15S)-6-(1H-INDOL-3-YLMETHYL)-9-(2-METHYLPROPYL)-2,5,8,11,14-PENTAOXO-12-PROPAN-2-YL-1,4,7,10,13-PENTAZABICYCLO(13.3.0)OCTADECAN-3-YL)ACETIC ACID;MFCD00133204;GTPL997;SCHEMBL1290617;DTXSID70929476;2-((3R,6R,9S,12R,15S)-6-(1H-indol-3-ylmethyl)-9-isobutyl-12-isopropyl-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazabicyclo(13.3.0)octadecan-3-yl)acetic acid;2-((3S,6R,9S,12R,15S)-6-(1H-indol-3-ylmethyl)-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazabicyclo(13.3.0)octadecan-3-yl)acetic acid;2-[(3R,6R,9S,12R,15S)-6-(1H-indol-3-ylmethyl)-9-isobutyl-12-isopropyl-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazabicyclo[13.3.0]octadecan-3-yl]acetic acid;2-[(3S,6R,9S,12R,15S)-6-(1H-indol-3-ylmethyl)-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazabicyclo[13.3.0]octadecan-3-yl]acetic acid;EX-A4062;BDBM50197954;HB3213;s7883;AKOS030526454;cyclo-(D-Trp-D-Asp-Pro-D-Val-Leu);BQ-123?;CCG-270231;CS-5694;DB12054;BQ-123, >=99%, lyophilized powder;cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu-);cyclo-(-D-Trp-D-Asp-Pro-D-Val-Leu);cyclo[-D-Asp-Pro-D-Val-Leu-D-Trp-];AC-36502;BS-15415;cyclo(L-Leu-D-Trp-D-Asp-L-Pro-D-Val);cyclo(L-Pro-D-Val-L-Leu-D-Trp-D-Asp);DA-51362;FB108394;HY-12378;cyclo(-D-Trp-D-Asp-L-Pro-D-Val-L-Leu);cyclo-(D-Trp-D-Asp-L-Pro-D-Val-L-Leu);cyclo-[D-Asp-L-Pro-D-Val-L-Leu-D-Trp-];NS00069585;BQ-123 Cyclo(-D-Trp-D-Asp-Pro-D-Val-Leu);C72461;Q4836304;Cyclo(D-a-aspartyl-L-prolyl-D-valyl-L-leucyl-D-tryptophyl);WDPVL (modifications: Trp-1 = D-Trp, Val-4 = D-Val, Cyclized);CYCLO(D-.ALPHA.-ASPARTYL-L-PROLYL-D-VALYL-L-LEUCYL-D-TRYPTOPHYL);[(3R,6S,9R,12R,17AS)-9-(1H-INDOL-3-YLMETHYL)-3-ISOPROPYL-6-(2-METHYLPROPYL)-1,4,7,10,13-PENTAOXO-DODECAHYDROPYRROLO[1,2-A]1,4,7,10,13-PENTAAZACYCLOPENTADECAN-12-YL]ACETIC ACID;
2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
3. The spatiotemporal control of signalling and trafficking of the GLP-1R
4. High fat diet and GLP-1 drugs induce pancreatic injury in mice
5. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
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