β-Casomorphin (1-2)
The antihypertensive peptide isolated from fermented milk had a low inhibitory activity against angiotensin I-converting enzyme (ACE), IC50 720 μM. The dipeptide is a possible biosynthetic precursor of endomorphin.
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| CAT# | C10001 |
| CAS | 51871-47-7 |
| Synonyms/Alias | beta-Casomorphin (1-2); b-Casomorphin (1-2); L-Tyrosyl-L-proline |
| Chemical Name | (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic acid |
| M.F/Formula | C14H18N2O4 |
| M.W/Mr. | 278.31 |
| Sequence | One Letter Code: YP
Three Letter Code: H-Tyr-Pro-OH |
| Appearance | White or off-white lyophilized powder |
| Activity | Inhibitor |
| Biological Activity | Tyr-Pro is a dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-proline. It derives from a L-tyrosine and a L-proline. |
| Storage | Store at -20°C |
Solubility | Soluble in DMSO |
Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
InChI | InChI=1S/C14H18N2O4/c15-11(8-9-3-5-10(17)6-4-9)13(18)16-7-1-2-12(16)14(19)20/h3-6,11-12,17H,1-2,7-8,15H2,(H,19,20)/t11-,12-/m0/s1 |
InChI Key | VNYDHJARLHNEGA-RYUDHWBXSA-N |
Canonical SMILES | C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)O |
Isomeric SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)O |
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