The antihypertensive peptide isolated from fermented milk had a low inhibitory activity against angiotensin I-converting enzyme (ACE), IC50 720 μM. The dipeptide is a possible biosynthetic precursor of endomorphin.
CAT No: C10001
CAS No: 51871-47-7
Synonyms/Alias: Tyr-pro;51871-47-7;L-Tyrosyl-L-proline;(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic Acid;tyrosyl-proline;CHEMBL1807689;CHEBI:141456;YP dipeptide;Y-P Dipeptide;H-Tyr-Pro-OH;Tyrosine Proline dipeptide;Tyrosine-Proline dipeptide;Tyrosyl-prolin;1-(2-Amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxylate;1-[2-Amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylate;(2S)-1-((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxylic acid;BETA-CASOMORPHIN (1-2);MFCD00236912;b-Casomorphin (1-2);alpha-Casomorphin (1-2);SCHEMBL5336562;DTXSID20430840;YP;BDBM50348856;AKOS010419272;FC108236;CS-0453191;EN300-22842740;Y-P;
Chemical Name: (2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic acid
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M.F/Formula | C14H18N2O4 |
M.W/Mr. | 278.3 |
Sequence | One Letter Code:YP Three Letter Code:H-Tyr-Pro-OH |
Appearance | White or off-white lyophilized powder |
Activity | Inhibitor |
Biological Activity | Tyr-Pro is a dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-proline. It derives from a L-tyrosine and a L-proline. |
Long-term Storage Conditions | Soluble in DMSO |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
InChI | InChI=1S/C14H18N2O4/c15-11(8-9-3-5-10(17)6-4-9)13(18)16-7-1-2-12(16)14(19)20/h3-6,11-12,17H,1-2,7-8,15H2,(H,19,20)/t11-,12-/m0/s1 |
InChI Key | VNYDHJARLHNEGA-RYUDHWBXSA-N |
Canonical SMILES | C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)O |
Isomeric SMILES | C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)O |
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