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β-Casomorphin (1-2)

The antihypertensive peptide isolated from fermented milk had a low inhibitory activity against angiotensin I-converting enzyme (ACE), IC50 720 μM. The dipeptide is a possible biosynthetic precursor of endomorphin.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
β-Casomorphin (1-2)(CAS 51871-47-7)

CAT No: C10001

CAS No:51871-47-7

Synonyms/Alias:Tyr-pro;51871-47-7;L-Tyrosyl-L-proline;(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic Acid;tyrosyl-proline;CHEMBL1807689;CHEBI:141456;YP dipeptide;Y-P Dipeptide;H-Tyr-Pro-OH;Tyrosine Proline dipeptide;Tyrosine-Proline dipeptide;Tyrosyl-prolin;1-(2-Amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxylate;1-[2-Amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylate;(2S)-1-((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxylic acid;BETA-CASOMORPHIN (1-2);MFCD00236912;b-Casomorphin (1-2);alpha-Casomorphin (1-2);SCHEMBL5336562;DTXSID20430840;YP;BDBM50348856;AKOS010419272;FC108236;CS-0453191;EN300-22842740;Y-P;

Chemical Name:(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxylic acid

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cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
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  • Drug master files (DMF) filing
M.F/Formula
C14H18N2O4
M.W/Mr.
278.3
Sequence
One Letter Code:YP
Three Letter Code:H-Tyr-Pro-OH
Appearance
White or off-white lyophilized powder
Activity
Inhibitor
Biological Activity
Tyr-Pro is a dipeptide obtained by formal condensation of the carboxy group of L-tyrosine with the amino group of L-proline. It derives from a L-tyrosine and a L-proline.
Long-term Storage Conditions
Soluble in DMSO
Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
InChI
InChI=1S/C14H18N2O4/c15-11(8-9-3-5-10(17)6-4-9)13(18)16-7-1-2-12(16)14(19)20/h3-6,11-12,17H,1-2,7-8,15H2,(H,19,20)/t11-,12-/m0/s1
InChI Key
VNYDHJARLHNEGA-RYUDHWBXSA-N
Canonical SMILES
C1CC(N(C1)C(=O)C(CC2=CC=C(C=C2)O)N)C(=O)O
Isomeric SMILES
C1C[C@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)O)N)C(=O)O

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