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Caspase-1/ICE Inhibitor Z-WEHD-FMK

Z-WEHD-FMK is an effective, cell-permeable and irreversible inhibitor of caspase-1, caspase-5 and cathepsin B (IC50 = 6 µM). It can inhibit apoptosis in multiple biological systems.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R0900

CAS No:210345-00-9

Synonyms/Alias:Caspase-1 inhibitor (fluoromethylketone), Caspase-5 inhibitor (fluoromethylketone)

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cGMP Peptide
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M.F/Formula
C37H42FN7O11
M.W/Mr.
763.78
Sequence
Z-Trp-Glu(OMe)-His-Asp(OMe)-fluoromethylketone
Labeling Target
Caspase-1/ Caspase-5
Purity
>99%
Activity
Inhibitor
Source#
Synthetic
Solubility
-20 °C
InChI
InChI=1S/C37H42FN7O10/c1-53-32(47)13-12-27(34(49)44-30(15-24-19-39-21-41-24)36(51)43-28(31(46)17-38)16-33(48)54-2)42-35(50)29(14-23-18-40-26-11-7-6-10-25(23)26)45-37(52)55-20-22-8-4-3-5-9-22/h3-11,18-19,21,27-30,40H,12-17,20H2,1-2H3,(H,39,41)(H,42,50)(H,43,51)(H,44,49)(H,45,52)/t27-,28-,29-,30-/m0/s1
InChI Key
NLZNSSWGRVBWIX-KRCBVYEFSA-N

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