Caspase Inhibitor I

Z-VAD(OMe)-FMK (Z-Val-Ala-Asp(OMe)-FMK) is a cell-permeable and irreversible pan-caspase inhibitor. Z-VAD(OMe)-FMK is an ubiquitin carboxy-terminal hydrolase L1 (UCHL1) inhibitor. Z-VAD(OMe)-FMK irreversibly modifies UCHL1 by targeting the active site of UCHL1.

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CAT#R1807
Chemical Structure
CAS187389-52-2
Synonyms/AliasZ-VAD (OMe)-FMK
M.F/FormulaC22H30FN3O7
M.W/Mr.467.49
SequenceOne Letter Code: ZVA-D(OMe)-FMK
Three Letter Code: Z-Val-Ala-Asp(OMe)-CH₂F
Labeling TargetPan-caspase
ApplicationZ-VAD-FMK is an irreversible, cell-permeable, broad-spectrum caspase inhibitor.
AppearanceWhite solid
Purity>98.0%
ActivityInhibitor
Areas of InterestCancer
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