Deltorphin I

Deltorphin I is an amphibian opioid peptide noted for its δ-receptor affinity and characteristic β-turn motif. Its sequence supports analyses of peptide folding and hydrophobic cluster formation. Researchers examine its interactions to define selectivity determinants. The molecule enriches studies on opioid-binding peptide architecture.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Deltorphin I(CAS 122752-15-2)

CAT No: D03015

CAS No:122752-15-2

Synonyms/Alias:Deltorphin I;Deltorphin C;122752-15-2;deltorphin I, Ala(2)-;Glycinamide, L-tyrosyl-D-alanyl-L-phenylalanyl-L-alpha-aspartyl-L-valyl-L-valyl-;H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2;CHEMBL317956;(3S)-3-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]-4-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-methyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-oxobutanoic acid;CHEBI:81500;DTXSID10153692;Delt-I;(Ala(2))deltorphin I;Tyr-ala-phe-asp-val-val-gly-NH2;Tyr-d-Ala-Phe-Asp-Val-Val-Gly-NH(2);Deltorphin 1; Deltorphin C;(D-Ala(2))-deltorphin-I;Deltophin 1;Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2;(3S)-3-(((2S)-2-(((2R)-2-(((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)amino)propanoyl)amino)-3-phenylpropanoyl)amino)-4-(((2S)-1-(((2S)-1-((2-amino-2-oxoethyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid;Deltorphin c(9ci);MFCD00080071;DELTORPHINI;DTXCID9076183;3-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{1-[1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid;HY-P1336;BDBM50001468;Tyr-D-Ala-Phe-Asp-Val-Val-GlyNH2;AKOS024458238;NCGC00167304-01;MS-31392;CS-0029459;C18097;Q5254879;(S)-3-((S)-2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-3-phenyl-propionylamino)-N-{(S)-1-[(S)-1-(carbamoylmethyl-carbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propyl}-succinamic acid;(S)-4-((S)-1-((S)-1-(2-amino-2-oxoethylamino)-3-methyl-1-oxobutan-2-ylamino)-3-methyl-1-oxobutan-2-ylamino)-3-((S)-2-((R)-2-((S)-2-amino-3-(4-hydroxyphenyl)propanamido)propanamido)-3-phenylpropanamido)-4-oxobutanoic acid;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C37H52N8O10
M.W/Mr.
768.9
Sequence
One Letter Code:YAFDVVG
Three Letter Code:H-Tyr-D-Ala-Phe-Asp-Val-Val-Gly-NH2
InChI
InChI=1S/C37H52N8O10/c1-19(2)30(36(54)40-18-28(39)47)45-37(55)31(20(3)4)44-35(53)27(17-29(48)49)43-34(52)26(16-22-9-7-6-8-10-22)42-32(50)21(5)41-33(51)25(38)15-23-11-13-24(46)14-12-23/h6-14,19-21,25-27,30-31,46H,15-18,38H2,1-5H3,(H2,39,47)(H,40,54)(H,41,51)(H,42,50)(H,43,52)(H,44,53)(H,45,55)(H,48,49)/t21-,25+,26+,27+,30+,31+/m1/s1
InChI Key
CJAORFIPPWIGPG-QXYJMILXSA-N

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