EBV (BZLF1)

    Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

    CAT No: PPO-H012

    Quick InquiryCustom Peptide Synthesis

    cGMP Peptide

    Registration of APIs CMC information required for an IND

    IND and NDA support Drug master files (DMF) filing

    Specification Technical Data Publications Customer reviews and Q&A
    ApplicationT-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
    Purity>70% (HPLC-MS)
    Areas of InterestInfection, Cancer, Hodgkin's lymphoma, Burkitt's lymphoma, Nasopharyngeal carcinoma, Dermatomyositis, Systemic lupus erythematosus, Rheumatoid arthritis, Sj?gren's syndrome, Multiple sclerosis
    Size1 vial containing 15 nmol ( 25μg) per peptide
    SwissProt IDP03206
    FormatFreeze dried in amber type glass vial
    NumberOfPeptides59
    OrganismEpstein-Barr virus (HHV-4)
    SpecificationsPeptide scan (15mers with 11 aa overlap)
    Protein Length245
    Protein NameTrans-activator protein BZLF1
    References1."PepMixTM Peptide Pools for Clinical Applications: T cell therapy for viral infections after hematopoietic stem cell transplant"
    Leen et al, Application Note (2012)
    2."Expansion of T Cells Targeting Multiple Antigens of Cytomegalovirus, Epstein – Barr Virus and Adenovirus to Provide Broad Antiviral Specificity After Stem Cell Transplantation". Hanley et al., Cytotherapy (2011)
    3."Rebound of Residual Plasma Viremia After Initial Decrease Following Addition of Intravenous Immunoglobulin to Effective Antiretroviral Treatment of HIV". Mellberg et al., AIDS Research and Therapy (2011)
    4."A Whole Blood Monokine-based Reporter Assay Provides a Sensitive and Robust Measurement of the Antigen-Specific T Cell Response"
    Chakera et al., Journal of Translational Medicine (2011)
    5."Adoptive Transfer of EBV-specific T Cells Results in Sustained Clinical Responses in Patients With Locoregional Nasopharyngeal Carcinoma". Louis et al., J Immunother (2010)
    6."Effective and Long-term Control of EBV PTLD After Transfer of Peptide-Selected T Cells". Moosmann et al., BLOOD (2010)
    7."Accelerated Production of Antigen-Specific T-cells for Pre-Clinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex)". Vera et al., J Immunother. (2010)
    8."Derivation of Human T Lymphocytes From Cord Blood and Peripheral Blood with Antiviral and Antileukemic Specificity from a Single Culture as Protection Against Infection and Relapse after Stem Cell Transplantation". Micklethwaite et al., Blood (2010)

    1. Tachykinin-related peptides modulate immune-gene expression in the mealworm beetle Tenebrio molitor L

    2. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate

    3. Cationic cell-penetrating peptides are potent furin inhibitors

    4. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function

    5. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

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