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EBV (BZLF1)

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: PPO-H012

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
Application
T-cell assays, Immune monitoring, Antigen specific T-cell stimulation, T-cell expansion, Cellular immune response
Purity
>70% (HPLC-MS)
Areas of Interest
Infection, Cancer, Hodgkin's lymphoma, Burkitt's lymphoma, Nasopharyngeal carcinoma, Dermatomyositis, Systemic lupus erythematosus, Rheumatoid arthritis, Sj?gren's syndrome, Multiple sclerosis
Size
1 vial containing 15 nmol ( 25μg) per peptide
SwissProt ID
P03206
Format
Freeze dried in amber type glass vial
NumberOfPeptides
59
Organism
Epstein-Barr virus (HHV-4)
Specifications
Peptide scan (15mers with 11 aa overlap)
Protein Length
245
Protein Name
Trans-activator protein BZLF1
References
1."PepMixTM Peptide Pools for Clinical Applications: T cell therapy for viral infections after hematopoietic stem cell transplant"
Leen et al, Application Note (2012)
2."Expansion of T Cells Targeting Multiple Antigens of Cytomegalovirus, Epstein – Barr Virus and Adenovirus to Provide Broad Antiviral Specificity After Stem Cell Transplantation". Hanley et al., Cytotherapy (2011)
3."Rebound of Residual Plasma Viremia After Initial Decrease Following Addition of Intravenous Immunoglobulin to Effective Antiretroviral Treatment of HIV". Mellberg et al., AIDS Research and Therapy (2011)
4."A Whole Blood Monokine-based Reporter Assay Provides a Sensitive and Robust Measurement of the Antigen-Specific T Cell Response"
Chakera et al., Journal of Translational Medicine (2011)
5."Adoptive Transfer of EBV-specific T Cells Results in Sustained Clinical Responses in Patients With Locoregional Nasopharyngeal Carcinoma". Louis et al., J Immunother (2010)
6."Effective and Long-term Control of EBV PTLD After Transfer of Peptide-Selected T Cells". Moosmann et al., BLOOD (2010)
7."Accelerated Production of Antigen-Specific T-cells for Pre-Clinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex)". Vera et al., J Immunother. (2010)
8."Derivation of Human T Lymphocytes From Cord Blood and Peripheral Blood with Antiviral and Antileukemic Specificity from a Single Culture as Protection Against Infection and Relapse after Stem Cell Transplantation". Micklethwaite et al., Blood (2010)

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