Edotreotide

Edotreotide is a chelated octreotide derivative with somatostatin activity. Edotreotide is produced by substituting tyrosine for phenylalanine at the 3 position of octreotide and chelated via dodecanetetraacetic acid (DOTA). Like octreotide, this edotreotide binds to somatostatin receptors (SSTRs), especially type 2, present on the cell membrane of many types of neuroendocrine tumors.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Edotreotide(CAS 204318-14-9)

CAT No: 10-101-210

CAS No:204318-14-9

Synonyms/Alias:DOTA-[TYR3]-OCTREOTIDE;DOTATOC;DOTA-FCYWKTCT-OL (DISULFIDE BRIDGE: 2-7);DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THR-OL (DISULFIDE BRIDGE: 2-7);[DOTA-DPHE1, TYR3]OCTREOTIDE;DOTA-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-THREONINOL;EDOTREOTIDE;4,7,10-TRICARBOXYMETHYL-1,4,7,10-TETRAAZA-CYCLODODECAN-1-YL-ACETYL-D-PHE-CYS-TYR-D-TRP-LYS-THR-CYS-L-THREONINOL, (DISULFIDE BOND)

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C65H92N14O18S2(netpeptide)
M.W/Mr.
1421.66
Sequence
Three Letter Code: DOTA-D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), cyclic disulfide
Biological Activity
Edotreotide is used in the Diagnosis and Staging of Tumors Expressing Somatostatin Receptors. It is an Indicator and Reagent.
Source#
Synthetic
Shipping Condition
Room temperature in continental US; may vary elsewhere.

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