Endomorphin-1 is an endogenous opioid tetrapeptide widely used to study μ-opioid receptor selectivity and signaling. Its compact structure facilitates high-resolution conformational analysis and β-turn formation. Researchers examine its aromatic and basic residues to understand binding determinants. The molecule contributes to neuropeptide design and receptor-docking models.
CAT No: E04001
Synonyms/Alias:Endomorphin 1;Endomorphin-1;189388-22-5;Tyr-Pro-Trp-Phe-Nh2;L-Phenylalaninamide, L-tyrosyl-L-prolyl-L-tryptophyl-;H-Tyr-Pro-Trp-Phe-NH2;(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide;tyrosyl-prolyl-tryptophyl-phenylalaninamide;CHEMBL316446;DTXSID10415505;MFCD01321063;(2S)-2-{[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]formamido}-N-[(1S)-1-carbamoyl-2-phenylethyl]-3-(1H-indol-3-yl)propanamide;(S)-1-(L-tyrosyl)-N-((S)-1-(((S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide;(S)-N-((S)-1-((S)-1-amino-1-oxo-3-phenylpropan-2-ylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-1-((S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidine-2-carboxamide;endomorphin -1;(2S)-1-((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)-N-((2S)-1-(((2S)-1-amino-1-oxo-3-phenylpropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide;(2S)-2-((((2S)-1-((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)(hydroxy)methylidene)amino)-N-((1S)-1-(C-hydroxycarbonimidoyl)-2-phenylethyl)-3-(1H-indol-3-yl)propanimidate;(2S)-2-(((2S)-1-((2S)-2-amino-3-(4-hydroxyphenyl)propanoyl)pyrrolidin-2-yl)formamido)-N-((1S)-1-carbamoyl-2-phenylethyl)-3-(1H-indol-3-yl)propanamide;(2S)-2-({[(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl](hydroxy)methylidene}amino)-N-[(1S)-1-(C-hydroxycarbonimidoyl)-2-phenylethyl]-3-(1H-indol-3-yl)propanimidate;YPWF-NH2;L-Phenylalaninamide,L-tyrosyl-L-prolyl-L-tryptophyl-;L-Tyrosyl-L-prolyl-L-tryptophyl-L-phenylalaninamide;GTPL1623;DTXCID00366355;CHEBI:177580;ZEXLJFNSKAHNFH-SYKYGTKKSA-N;C34H38N6O5;HY-P0185;BDBM50095155;HB2410;AKOS024456355;NCGC00163676-01;NCGC00163676-02;AS-80638;DA-52894;G78409;Q4531852;(S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide;1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-((S)-(S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide;1-[2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide;
2. High fat diet and GLP-1 drugs induce pancreatic injury in mice
3. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
4. The spatiotemporal control of signalling and trafficking of the GLP-1R
5. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
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