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Endothelin-2, human

Endothelin-2, human is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors, ET-RA and ET-RB.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1341

CAS No:123562-20-9

Synonyms/Alias:123562-20-9;Endothelin-2 (human, canine);Human endothelin-2;Endothelin-2, human;Endothelin-2 (Human);PED-4209-S;AKOS034831531;Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp;L023974;Q27077186;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C115H160N26O32S4
M.W/Mr.
2546.9
Sequence
One Letter Code:CSCSSWLDKECVYFCHLDXXW
Three Letter Code:H-DL-Cys(1)-DL-Ser-DL-Cys(2)-DL-Ser-DL-Ser-DL-Trp-DL-Leu-DL-Asp-DL-Lys-DL-Glu-DL-Cys(2)-DL-Val-DL-Tyr-DL-Phe-DL-Cys(1)-DL-His-DL-Leu-DL-Asp-DL-xiIle-DL-xiIle-DL-Trp-OH
Length
21
InChI
InChI=1S/C115H160N26O32S4/c1-11-59(9)93(113(170)132-82(115(172)173)41-64-46-120-71-27-19-17-25-68(64)71)141-114(171)94(60(10)12-2)140-105(162)81(44-91(150)151)130-99(156)75(37-57(5)6)125-103(160)79(42-65-47-118-55-121-65)128-109(166)86-52-175-174-51-69(117)95(152)133-83(48-142)108(165)138-87-53-176-177-54-88(111(168)139-92(58(7)8)112(169)131-77(39-62-29-31-66(145)32-30-62)100(157)126-76(101(158)137-86)38-61-22-14-13-15-23-61)136-97(154)73(33-34-89(146)147)123-96(153)72(28-20-21-35-116)122-104(161)80(43-90(148)149)129-98(155)74(36-56(3)4)124-102(159)78(40-63-45-119-70-26-18-16-24-67(63)70)127-106(163)84(49-143)134-107(164)85(50-144)135-110(87)167/h13-19,22-27,29-32,45-47,55-60,69,72-88,92-94,119-120,142-145H,11-12,20-21,28,33-44,48-54,116-117H2,1-10H3,(H,118,121)(H,122,161)(H,123,153)(H,124,159)(H,125,160)(H,126,157)(H,127,163)(H,128,166)(H,129,155)(H,130,156)(H,131,169)(H,132,170)(H,133,152)(H,134,164)(H,135,167)(H,136,154)(H,137,158)(H,138,165)(H,139,168)(H,140,162)(H,141,171)(H,146,147)(H,148,149)(H,150,151)(H,172,173)
InChI Key
MLFJHYIHIKEBTQ-UHFFFAOYSA-N

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