GLYX 13

Name: GLYX 13
Brand: Creative Peptides
SKU: R0954
Availability: MadeToOrder

Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist.

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CAT No: R0954

CAS No: 117928-94-6

Synonyms/Alias: Rapastinel;117928-94-6;GLYX 13;GLYX-13;GLYX13;TPPT-amide;Rapastinelum;GLYX-13 peptide;UNII-6A1X56B95E;L-Threoninamide, L-threonyl-L-prolyl-L-prolyl-;Rapastinel [USAN:INN];GLYX-13 trifluoroacetate;RAPASTINEL [INN];RAPASTINEL [USAN];RAPASTINEL [WHO-DD];6A1X56B95E;(2S)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]-N-[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]pyrrolidine-2-carboxamide;(S)-N-((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)-1-((S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide;L-THREONYL-L-PROLYL-L-PROLYL-L-THREONINAMIDE;(2S,3R)-2-(((2S)-1-((2S)-1-((2S,3R)-2-amino-3-hydroxybutanoyl)pyrrolidine-2-carbonyl)pyrrolidin-2-yl)formamido)-3-hydroxybutanamide;(2S,3R)-2-{[(2S)-1-[(2S)-1-[(2S,3R)-2-amino-3-hydroxybutanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}-3-hydroxybutanamide;GLYX13;Rapastinel;Rapastinel (GLYX-13);Rapastinel(GLYX-13)?;TPPT-amide trifluoroacetate;SCHEMBL1668190;CHEMBL3544917;EX-A794;GIBQQARAXHVEGD-BSOLPCOYSA-N;DTXSID501030481;MFCD12912477;MFCD20527320;s6907;AKOS024457610;CS-5507;DB11801;NCGC00485669-01;AC-32874;AS-55920;HY-16728;NS00072942;Q5513673;BRD-K02206208-001-01-4;L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate; Thr-Pro-Pro-Thr-NH2 trifluoroacetate;

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C18H31N5O6
M.W/Mr.	413.5
Sequence	One Letter Code:TPPT Three Letter Code:H-Thr-Pro-Pro-Thr-NH2
Biological Activity	NMDA receptor partial agonist that acts at the glycine site. Simultaneously acts as a promoter of the induction of long-term potentiation (LTP) and as a suppressor of long-term depression (LTD). Exhibits nootropic, neuroprotective and antinociceptive activity, and enhances learning, memory and cognition in vivo. Brain penetrant.

Long-term Storage Conditions	Soluble to 2 mg/ml in water
Shipping Condition	Room temperature in continental US; may vary elsewhere.
InChI	InChI=1S/C18H31N5O6/c1-9(24)13(19)18(29)23-8-4-6-12(23)17(28)22-7-3-5-11(22)16(27)21-14(10(2)25)15(20)26/h9-14,24-25H,3-8,19H2,1-2H3,(H2,20,26)(H,21,27)/t9-,10-,11+,12+,13+,14+/m1/s1
InChI Key	GIBQQARAXHVEGD-BSOLPCOYSA-N

1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists

2. Urinary Metabolites Associated with Blood Pressure on a Low-or High-Sodium Die

3. cRGD-functionalized, DOX-conjugated, and 64Cu-labeled superparamagnetic iron oxide nanoparticles for targeted anticancer drug delivery and PET/MR imaging

4. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

5. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

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