GPLGIAGQ

GPLGIAGQ, a MMP2-cleavable polypeptide, is used as a stimulus-sensitive linker in both liposomal and micellar nanocarriers for MMP2-triggered tumor targeting.

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CAT No: 10-101-303

CAS No: 109053-09-0

Synonyms/Alias: GPLGIAGQ;109053-09-0;L-Glutamine, glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-;(2S)-5-amino-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[2-[[(2S)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-5-oxopentanoic acid;Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln;HY-P2213;DA-73847;CS-0113488;Glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-glutamine;

Chemical Name: (2S)-5-amino-2-[[2-[[(2S)-2-[[(2S,3S)-2-[[2-[[(2S)-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]acetyl]amino]-5-oxopentanoic acid

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C31H53N9O10
M.W/Mr.	711.8
Sequence	One Letter Code:GPLGIAGQ Three Letter Code:H-Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln-OH
Purity	≥97% (HPLC)

Long-term Storage Conditions	10 mM in DMSO
Shipping Condition	+20°C (International: -20°C)
InChI	InChI=1S/C31H53N9O10/c1-6-17(4)26(30(48)36-18(5)27(45)34-14-23(42)37-19(31(49)50)9-10-22(33)41)39-24(43)15-35-28(46)20(12-16(2)3)38-29(47)21-8-7-11-40(21)25(44)13-32/h16-21,26H,6-15,32H2,1-5H3,(H2,33,41)(H,34,45)(H,35,46)(H,36,48)(H,37,42)(H,38,47)(H,39,43)(H,49,50)/t17-,18-,19-,20-,21-,26-/m0/s1
InChI Key	BLNMYSBCIVAVFK-PFZXUFBWSA-N
Canonical SMILES	CCC(C)C(C(=O)NC(C)C(=O)NCC(=O)NC(CCC(=O)N)C(=O)O)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C1CCCN1C(=O)CN
Isomeric SMILES	CC[C@H](C)[C@@H](C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H]1CCCN1C(=O)CN

1. Urinary Metabolites Associated with Blood Pressure on a Low-or High-Sodium Die

2. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency

3. Constitutive and inflammation-dependent antimicrobial peptides produced by epithelium are differentially processed and inactivated by the commensal Finegoldia magna and the pathogen Streptococcus pyogenes

4. Spatiotemporal delivery of nanoformulated liraglutide for cardiac regeneration after myocardial infarction

5. Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation

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GPLGIAGQ

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