Hexapeptide-11

Hexapeptide-11 is a bioengineered peptide composed of six amino acids, designed for use in cosmetic formulations targeting skin conditioning and anti-aging applications. It is valued for its ability to help support the skin's natural processes, including elasticity and firmness. Suitable for inclusion in a wide range of topical products, Hexapeptide-11 is compatible with global cosmetic regulations and offers formulators a versatile option for innovative skincare solutions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1625

CAS No:100684-36-4

Synonyms/Alias:Hexapeptide-11;161258-30-6;Fvapfp;Peptamide 6;Phe-val-ala-pro-phe-pro;Hexapeptide-11 [INCI];L-Proline, L-phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-;UNII-NCJ63WU6BY;NCJ63WU6BY;(2S)-1-[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-3-methylbutanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carboxylic acid;Hexapeptide-11 (acetate);L-Phenylalanyl-L-valyl-L-alanyl-L-prolyl-L-phenylalanyl-L-proline;SCHEMBL25122503;DTXSID90648379;HY-P2096;AT41883;DA-74113;FH146807;CS-0108175;Q27284797;

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C36H48N6O7
M.W/Mr.
676.8
Sequence
One Letter Code:FVAPFP
Three Letter Code:H-Phe-Val-Ala-Pro-Phe-Pro-OH
Functions
Hexapeptide-11 can induce the activity of extracellular MMPs and suppress cell migration. It helps reduce wrinkles, combat skin-aging and improve the skin elasticity.

Mechanism of Action (MOA)

Hexapeptide-11 is a bioactive oligopeptide that interacts with cellular signaling pathways involved in proteostasis and extracellular matrix modulation. By mimicking specific amino acid sequences, Hexapeptide-11 may influence the activity of proteasome-related enzymes and support the natural turnover of structural proteins. This peptide's biochemical interactions can contribute to maintaining an optimal cellular environment, aligning with the skin's intrinsic renewal and homeostasis processes.

Hexapeptide-11 can be incorporated into a variety of cosmetic formulations to enhance product offerings and texture.

- Suitable for use in facial serums and emulsions
- Can be added to anti-aging creams and lotions
- Compatible with eye contour products
- Appropriate for hair care formulations, including conditioners and masks
- May be included in sheet masks and leave-on treatments
- Stable in both water-based and emulsion systems

INCIName
Hexapeptide-11
InChI
InChI=1S/C36H48N6O7/c1-22(2)30(40-31(43)26(37)20-24-12-6-4-7-13-24)33(45)38-23(3)34(46)41-18-10-16-28(41)32(44)39-27(21-25-14-8-5-9-15-25)35(47)42-19-11-17-29(42)36(48)49/h4-9,12-15,22-23,26-30H,10-11,16-21,37H2,1-3H3,(H,38,45)(H,39,44)(H,40,43)(H,48,49)/t23-,26-,27-,28-,29-,30-/m0/s1
InChI Key
GFEYWOGCSROPRT-OBXVVNIGSA-N
References
Peptamide 6; Vital Hair and Scalp Complex

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