HexaPeptide-3

HexaPeptide-3 is a synthetic peptide composed of six amino acids, designed for use in cosmetic formulations targeting the appearance of fine lines and wrinkles. By supporting skin conditioning and enhancing the overall feel of topical products, HexaPeptide-3 is suitable for inclusion in a range of anti-aging skincare applications. Its compatibility with various formulation types allows for flexible integration into creams, serums, and emulsions.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPC1642

Synonyms/Alias:Hexapeptide-3;1205679-02-2;SCHEMBL20827629;HY-P5254;DA-64127;CS-0863863;(4S)-4-amino-5-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C35H62N14O11S
M.W/Mr.
887
Sequence
Three Letter Code: Pal-Gly-His-Lys-OH

Mechanism of Action (MOA)

HexaPeptide-3 is a synthetic signal peptide composed of six amino acids. It interacts with neuronal SNARE complex proteins, modulating vesicular release mechanisms within the skin. By influencing neurotransmitter signaling pathways, HexaPeptide-3 supports the maintenance of optimal cellular communication. This peptide's activity is associated with the regulation of skin's homeostatic processes, contributing to a balanced extracellular environment without altering physiological or therapeutic endpoints. Suitable for inclusion in topical cosmetic formulations.

HexaPeptide-3 is suitable for incorporation into a variety of cosmetic formulations.

- Recommended for use in facial serums and creams
- Compatible with eye contour products
- Can be added to lightweight lotions and gels
- Suitable for daily skincare routines
- Easily integrated into both water-based and emulsion systems
- Ideal for leave-on formulations

Shipping Condition
Room temperature in continental US; may vary elsewhere.

Useful Tools

Peptide Calculator

Abbreviation List

Peptide Glossary

If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.

Featured Services
Custom Conjugation ServicePeptide Modification ServicesEpitope Mapping ServicesPeptide Nucleic Acids SynthesisPeptide Analysis ServicescGMP Peptide ServicePeptide CDMOPeptide Synthesis Services
Hot Products
About us

Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.

From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.

Our Customers