iRGD peptide

iRGD peptide is a 9-amino acid cyclic peptide, triggers tissue penetration of drugs by first binding to av integrins, then proteolytically cleaved in the tumor to produce CRGDK/R to interact with neuropilin-1, and has tumor-targeting and tumor-penetrating properties.

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CAT#R1458
CAS1392278-76-0
Synonyms/Aliasc(CRGDKGPDC)
M.F/FormulaC35H57N13O14S2
M.W/Mr.948.04
SequenceOne Letter Code: CRGDKGPDC)
Three Letter Code: Cys-Arg-Gly-Asp-Lys-Gly-Pro-Asp-Cys
ApplicationiRGD peptides have been shown to increase the accumulation and penetration of anticancer drugs in tumors, but not into normal tissues-regardless of whether the drug is coupled to or administered with the peptide.
Purity98%
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