KAI-1678 is an inhibitor of epsilon protein kinase C in the treatment of neuropathic pain in patients with PHN.
CAT# | 10-101-144 |
M.F/Formula | C107H191N43O29S2 |
M.W/Mr. | 2522 |
Sequence | H-Cys(1)-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH. H-Cys(1)-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH |
Labeling Target | Epsilon protein kinase C (εPKC) |
Activity | Inhibitor |
Biological Activity | KAI-1678 is a synthetic 21-amino acid, cell-permeable peptide composed of an active inhibitor of εPKC conjugated to a carrier peptide to aid delivery to the targeted intracellular site of action. |
Areas of Interest | Neurological Disease |
Disease | Postherpetic neuralgia (PHN); Postoperative pain; Spinal cord injury; Neuropathic pain |
Target | εPKC |
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