KAI-1678

KAI-1678 is an inhibitor of epsilon protein kinase C in the treatment of neuropathic pain in patients with PHN.

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CAT#10-101-144
M.F/FormulaC107H191N43O29S2
M.W/Mr.2522
SequenceH-Cys(1)-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH. H-Cys(1)-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH
Labeling TargetEpsilon protein kinase C (εPKC)
ActivityInhibitor
Biological ActivityKAI-1678 is a synthetic 21-amino acid, cell-permeable peptide composed of an active inhibitor of εPKC conjugated to a carrier peptide to aid delivery to the targeted intracellular site of action.
Areas of InterestNeurological Disease
DiseasePostherpetic neuralgia (PHN); Postoperative pain; Spinal cord injury; Neuropathic pain
TargetεPKC
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