L-Lactolactoyl-Phe-Octreotide introduces a lactoyl moiety on phenylalanine within the octreotide framework, increasing polarity and hydrogen-bonding capacity. Researchers analyze shifts in conformational preferences and receptor-binding features. The modification influences solubility and matrix interactions. Applications include modified-analogue evaluation, biophysical analysis, and peptide-ligand engineering.
CAT No: Z10-101-214
Synonyms/Alias:(N-L-Lactolactoyl)-D-Phenylalanyl-L-hemicystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-hemicystyl-L-Threoninol cyclic(27)-disulfide; (R)-1-(((R)-1-(((4R,7S,10S,13R,16S,19R)-13-((1H-indol-3-yl)methyl)-10-(4-aminobutyl)-16-benzyl-4-(((2R,3R)-1,3-dihydroxybutan-2-yl)carbamoyl)-7-((R)-1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-19-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl(R)-2-hydroxypropanoate
1. Cell-based adhesion assays for isolation of snake venom’s integrin antagonists
3. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
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