L-Thyroxine

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP19301

CAS No:51-48-9

Synonyms/Alias:L-thyroxine;levothyroxine;synthroid;thyroxin;Thyrax;51-48-9;Tetraiodothyronine;Thyratabs;Thyreoideum;Thyroxinal;Thyroxineiodine;thyroxine;3,3',5,5'-Tetraiodo-L-thyronine;Levoxyl;(-)-Thyroxine;L-Thyroxin;Levothyroxin;levothroid;Levothyroxinesodium;Thyroxine(l);Laevothyroxinum;L-T4;3,5,3',5'-Tetraiodo-L-thyronine;DL-Thyroxin;3,5,3',5'-Tetraiodothyronine

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Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.F/Formula

C15H11I4NO4

M.W/Mr.

776.87

Abbr

L-Thyroxine

InChI

1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)/t12-/m0/s1

InChI Key

XUIIKFGFIJCVMT-LBPRGKRZSA-N

Canonical SMILES

C1=C(C=C(C(=C1I)OC2=CC(=C(C(=C2)I)O)I)I)CC(C(=O)O)N

1. TMEM16F and dynamins control expansive plasma membrane reservoirs

2. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis

3. Myotropic activity and immunolocalization of selected neuropeptides of the burying beetle Nicrophorus vespilloides (Coleoptera: Silphidae)

4. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

5. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

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