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LZ1 peptide

LZ1 peptide is a cationic, amphipathic sequence often investigated for membrane-permeabilizing and antimicrobial-like properties in model systems. Hydrophobic residues align to form a nonpolar face, while lysine and arginine build a positively charged interface. Researchers evaluate helical content in lipid environments and vesicle-disruption efficiency. Applications span host-defense peptide modeling, surface-coating studies, and biophysical interaction analysis.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R2724

Synonyms/Alias:LZ1 peptide;HY-P10338;CS-1051170

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C113H167N33O15
M.W/Mr.
2227.7
Sequence
One Letter Code:VKRWKKWWRKWKKWV
Three Letter Code:H-Val-Lys-Arg-Trp-Lys-Lys-Trp-Trp-Arg-Lys-Trp-Lys-Lys-Trp-Val-NH2
InChI
InChI=1S/C113H167N33O15/c1-65(2)95(120)111(161)140-87(44-20-26-52-119)100(150)136-89(46-28-54-127-113(124)125)105(155)142-91(56-68-61-129-78-35-11-6-30-73(68)78)107(157)138-82(39-15-21-47-114)98(148)133-84(41-17-23-49-116)103(153)143-93(58-70-63-131-80-37-13-8-32-75(70)80)109(159)145-92(57-69-62-130-79-36-12-7-31-74(69)79)108(158)139-88(45-27-53-126-112(122)123)101(151)135-85(42-18-24-50-117)102(152)141-90(55-67-60-128-77-34-10-5-29-72(67)77)106(156)137-83(40-16-22-48-115)99(149)134-86(43-19-25-51-118)104(154)144-94(110(160)146-96(66(3)4)97(121)147)59-71-64-132-81-38-14-9-33-76(71)81/h5-14,29-38,60-66,82-96,128-132H,15-28,39-59,114-120H2,1-4H3,(H2,121,147)(H,133,148)(H,134,149)(H,135,151)(H,136,150)(H,137,156)(H,138,157)(H,139,158)(H,140,161)(H,141,152)(H,142,155)(H,143,153)(H,144,154)(H,145,159)(H,146,160)(H4,122,123,126)(H4,124,125,127)/t82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-/m0/s1
InChI Key
AEGLGCLRXLHQRT-YZCAGTBWSA-N

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