This peptide corresponds to the membrane-permeable sequence designed from the carboxyl terminus of Gα subunits targeting G protein subunits. This is a membrane-translocating hydrophobic sequence derived specifically from the h-region of a signal peptide sequence of K-FGF (Kaposi fibroblast growth factor).
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M.F/Formula | C75H135N17O17 |
M.W/Mr. | 1547 |
Sequence | H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Lys-OH |
1. Cationic cell-penetrating peptides are potent furin inhibitors
2. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
3. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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