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Met-Enkephalin-Arg-Phe

Met-Enkephalin-Arg-Phe extends the native enkephalin sequence with additional residues influencing binding and folding. The peptide supports research into receptor selectivity, aromatic stacking, and hydrophobic clustering. Researchers employ it to analyze extended opioid-like motifs. Its defined architecture aids structural investigations.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Met-Enkephalin-Arg-Phe(CAS 73024-95-0)

CAT No: PI-013

CAS No:73024-95-0

Synonyms/Alias:Met-enkephalin-Arg-Phe;73024-95-0;Tyr-gly-gly-phe-met-arg-phe;Yggfmrf;Met-enk-AP;Enkephalin met, heptapeptide;6-Arg-7-phe-met-enkephalin;Met-enkephalin, arg(6)-phe(7)-;enkephalin-Met, Arg(6)-Phe(7)-;Methionine-enkephalin, arg(6)-phe(7)-;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoic acid;Enkephalin-met, arginyl(6)-phenylalanine(7)-;Methionine-enkephalin-arginine-phenylalanine;Tyrosyl-glycyl-glycyl-phenylalanyl-methionyl-arginyl-phenylalanine;L-Phenylalanine, N-(N(2)-(N-(N-(N-(N-L-tyrosylglycyl)glycyl)-L-phenylalanyl)-l-methionyl)-L-arginyl)-;MEAP peptide;MERF peptide;H-Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH;MFCD00076425;CHEBI:80265;HY-P4196;DA-55364;FM108789;PD150438;CS-0647109;H-Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH; H-YGGFMRF-OH;Met-Enkephalin-Arg-Phe (H-L-Tyr-Gly-Gly-L-Phe-L-Met-L-Arg-L-Phe-OH);(2S,5S,8S,11S,20S)-20-amino-2,11-dibenzyl-5-(3-guanidinopropyl)-21-(4-hydroxyphenyl)-8-(2-(methylthio)ethyl)-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazahenicosan-1-oic acid;

Chemical Name:(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C42H56N10O9S
M.W/Mr.
877
Sequence
One Letter Code:YGGFMRF
Three Letter Code:H-Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH
InChI
InChI=1S/C42H56N10O9S/c1-62-20-18-32(39(58)50-31(13-8-19-46-42(44)45)38(57)52-34(41(60)61)23-27-11-6-3-7-12-27)51-40(59)33(22-26-9-4-2-5-10-26)49-36(55)25-47-35(54)24-48-37(56)30(43)21-28-14-16-29(53)17-15-28/h2-7,9-12,14-17,30-34,53H,8,13,18-25,43H2,1H3,(H,47,54)(H,48,56)(H,49,55)(H,50,58)(H,51,59)(H,52,57)(H,60,61)(H4,44,45,46)/t30-,31-,32-,33-,34-/m0/s1
InChI Key
KTQKWSPZOZKAEE-LJADHVKFSA-N
Canonical SMILES
CSCCC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N
Isomeric SMILES
CSCC[C@@H](C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)[C@H](CC3=CC=C(C=C3)O)N

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