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α-MSH (free acid)

α-MSH (free acid) is a melanocortin peptide containing aromatic and charged residues that shape conformational and receptor-binding properties. Its acidic terminus influences solubility and structural modeling. The sequence supports spectroscopic analysis. Researchers apply it in biochemical studies of melanotropic peptide signaling.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: M2701

CAS No:10466-28-1

Synonyms/Alias:13-Val-alpha-msh (1-13);10466-28-1;alpha-Msh(1-13),valine(13)-;alpha-Msh (1-13), val(13)-;alpha-Melanotropin (pig), 13-L-valine-;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C77H108N20O20S
M.W/Mr.
1665.9
Sequence
One Letter Code:SYSMEHFRWGKPV
Three Letter Code:Ac-Ser-Tyr-Ser-Met-Glu-DL-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH
InChI
InChI=1S/C77H108N20O20S/c1-42(2)64(76(116)117)96-74(114)61-20-13-30-97(61)75(115)54(18-10-11-28-78)87-62(102)38-84-65(105)57(34-46-36-83-50-17-9-8-16-49(46)50)93-66(106)51(19-12-29-82-77(79)80)88-69(109)55(32-44-14-6-5-7-15-44)91-71(111)58(35-47-37-81-41-85-47)94-67(107)52(25-26-63(103)104)89-68(108)53(27-31-118-4)90-73(113)60(40-99)95-70(110)56(33-45-21-23-48(101)24-22-45)92-72(112)59(39-98)86-43(3)100/h5-9,14-17,21-24,36-37,41-42,51-61,64,83,98-99,101H,10-13,18-20,25-35,38-40,78H2,1-4H3,(H,81,85)(H,84,105)(H,86,100)(H,87,102)(H,88,109)(H,89,108)(H,90,113)(H,91,111)(H,92,112)(H,93,106)(H,94,107)(H,95,110)(H,96,114)(H,103,104)(H,116,117)(H4,79,80,82)/t51-,52-,53-,54-,55-,56-,57-,58?,59-,60-,61-,64-/m0/s1
InChI Key
MBBQINYFFIKILA-PDEGJNOBSA-N

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