N-α-Z-N-ε-tosyl-L-lysine dicyclohexylamine salt

N-α-Z-N-ε-tosyl-L-lysine dicyclohexylamine salt is a protected lysine derivative featuring an Nα-benzyloxycarbonyl (Z/Cbz-type) carbamate at the α-amino group and an Nε-tosyl (tosylsulfonamide) protecting group on the ε-amino group, with the lysine backbone retaining a free carboxyl group. The molecule is present as a dicyclohexylamine salt, and its side chain contains the protected ε-nitrogen while the α-amino functionality is masked by the Z group, yielding a zwitterionic salt-forming profile driven by the carboxylate. This salt-form, along with the dual N-protection pattern, is used as a peptide-building block in peptide synthesis workflows where controlled chemoselectivity is required for stepwise assembly and for minimizing side reactions associated with unprotected amines.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01461

CAS No:2362-45-0

Synonyms/Alias:ZINC19865111;L-Lysine,N6-[(4-methylphenyl)sulfonyl]-N2-[(phenylmethoxy)carbonyl]-

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M.F/Formula
C21H26N2O6S
M.W/Mr.
615.8
Abbr
Z-Lys(Tos)-OH.DCHA
InChI
1S/C21H26N2O6S/c1-16-10-12-18(13-11-16)30(27,28)22-14-6-5-9-19(20(24)25)23-21(26)29-15-17-7-3-2-4-8-17/h2-4,7-8,10-13,19,22H,5-6,9,14-15H2,1H3,(H,23,26)(H,24,25)/t19-/m0/s1
InChI Key
YHLJTFYIMBJHBB-IBGZPJMESA-N
Canonical SMILES
CC1=CC=C(C=C1)S(=O)(=O)NCCCCC(C(=O)O)NC(=O)OCC2=CC=CC=C2

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