1-Naphthalenylsulfonyl-Ile-Trp-aldehyde is a synthetic small molecule used in protease activity assays, incorporating a naphthalene-based fluorescent tag. The aldehyde group enables covalent attachment to nucleophilic residues in active sites, facilitating the study of enzyme mechanisms. Its structure supports real-time monitoring of proteolytic cleavage and enzymatic specificity. Researchers use it for biochemical assays to track enzyme inhibition and substrate specificity.
1. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
2. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
3. High fat diet and GLP-1 drugs induce pancreatic injury in mice
5. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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