O-tert.Butyl-L-threonine is an L-threonine-derived amino acid derivative in which the threonine side-chain hydroxyl is converted to an O-tert-butyl ether, yielding a protected, non-free alcohol functionality while retaining the amino acid backbone. The molecule contains an α-amino group and a carboxyl group along with an ether-protected β-hydroxy side chain, and its stereochemistry is specified as L at the α-carbon by the product name. In peptide and amino acid synthesis workflows, this O-tert-butyl protection pattern is employed to control chemoselectivity by suppressing side-chain hydroxyl reactivity during coupling or other transformations, and the compound can serve as a precursor to threonine-containing intermediates after deprotection.
CAT No: CP01934
CAS No:4378-13-6
Synonyms/Alias:O-tert-Butyl-L-threonine;4378-13-6;H-Thr(tBu)-OH;(2S,3R)-2-Amino-3-(tert-butoxy)butanoicacid;(2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]butanoicacid;O-tert-Butyl-L-allo-threonine;AC1OCVO1;O-tert.Butyl-L-threonine;H-THR-OH;Ambcb4034712;20644_ALDRICH;SCHEMBL561539;20644_FLUKA;CTK3J1682;MolPort-003-927-730;NMJINEMBBQVPGY-RITPCOANSA-N;H-Ser(Trt)-2-ChlorotritylResin;H-Thr(tBu)-2-ChlorotritylResin;ZINC404775;ANW-30023;AKOS006238375;AM82267;RTR-016972;AJ-22415;AK-45262
1. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
5. Emu oil in combination with other active ingredients for treating skin imperfections
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