Palmitoyl tetrapeptide-10

Palmitoyl tetrapeptide-10 is a synthetic peptide consisting of four amino acids linked to a palmitic acid chain, designed for use in cosmetic formulations. Recognized for its compatibility with skin care and anti-aging products, it supports the maintenance of skin's structural integrity by promoting optimal skin condition. Palmitoyl tetrapeptide-10 is suitable for inclusion in a variety of topical applications, offering formulators flexibility in product development.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Palmitoyl tetrapeptide-10(CAS 887140-79-6)

CAT No: CPO-003

CAS No:887140-79-6

Synonyms/Alias:Palmitoyl tetrapeptide-10;887140-79-6;N-Palmitoyl-Lys-Thr-Phe-Lys;6Q6H1PKC05;UNII-6Q6H1PKC05;Palmitoyl tetrapeptide-10 [INCI];L-Lysine, N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-phenylalanyl-;(2S)-6-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid;SCHEMBL21436697;HY-P5269;AT41881;DA-56570;CS-0863962;

Chemical Name:(2S)-6-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C41H72N6O7
M.W/Mr.
761
Sequence
One Letter Code:KTFK
Three Letter Code:palmitoyl-Lys-Thr-Phe-Lys-OH

Mechanism of Action (MOA)

Palmitoyl tetrapeptide-10 is a synthetic signal peptide conjugated to a palmitic acid moiety for enhanced skin penetration. It interacts with cellular communication pathways by modulating the activity of key extracellular matrix proteins. Through biochemical signaling, it supports the maintenance of skin's structural integrity by influencing the expression of matrix components such as collagen and fibronectin, contributing to an optimized extracellular environment. This mechanism is compatible with topical cosmetic applications.

Palmitoyl tetrapeptide-10 is suitable for incorporation into a variety of cosmetic formulations. Typical application directions include:

- Facial serums for daily skincare routines
- Lightweight emulsions and lotions
- Eye contour creams and gels
- Leave-on masks and overnight treatments
- Sheet masks and hydrogel patches
- Pre-makeup primers and base products

InChI
InChI=1S/C41H72N6O7/c1-3-4-5-6-7-8-9-10-11-12-13-14-18-27-36(49)44-33(25-19-21-28-42)38(50)47-37(31(2)48)40(52)46-35(30-32-23-16-15-17-24-32)39(51)45-34(41(53)54)26-20-22-29-43/h15-17,23-24,31,33-35,37,48H,3-14,18-22,25-30,42-43H2,1-2H3,(H,44,49)(H,45,51)(H,46,52)(H,47,50)(H,53,54)/t31-,33+,34+,35+,37+/m1/s1
InChI Key
XCEMXBAGNZCOHW-JPZUFNMASA-N
Canonical SMILES
CCCCCCCCCCCCCCCC(=O)NC(CCCCN)C(=O)NC(C(C)O)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCCCN)C(=O)O
Isomeric SMILES
CCCCCCCCCCCCCCCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCCCN)C(=O)O

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