Palmitoyl tetrapeptide-10 is a synthetic peptide consisting of four amino acids linked to a palmitic acid chain, designed for use in cosmetic formulations. Recognized for its compatibility with skin care and anti-aging products, it supports the maintenance of skin's structural integrity by promoting optimal skin condition. Palmitoyl tetrapeptide-10 is suitable for inclusion in a variety of topical applications, offering formulators flexibility in product development.
CAT No: CPO-003
CAS No:887140-79-6
Synonyms/Alias:Palmitoyl tetrapeptide-10;887140-79-6;N-Palmitoyl-Lys-Thr-Phe-Lys;6Q6H1PKC05;UNII-6Q6H1PKC05;Palmitoyl tetrapeptide-10 [INCI];L-Lysine, N2-(1-oxohexadecyl)-L-lysyl-L-threonyl-L-phenylalanyl-;(2S)-6-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid;SCHEMBL21436697;HY-P5269;AT41881;DA-56570;CS-0863962;
Chemical Name:(2S)-6-amino-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid
Mechanism of Action (MOA)
Palmitoyl tetrapeptide-10 is a synthetic signal peptide conjugated to a palmitic acid moiety for enhanced skin penetration. It interacts with cellular communication pathways by modulating the activity of key extracellular matrix proteins. Through biochemical signaling, it supports the maintenance of skin's structural integrity by influencing the expression of matrix components such as collagen and fibronectin, contributing to an optimized extracellular environment. This mechanism is compatible with topical cosmetic applications.
Palmitoyl tetrapeptide-10 is suitable for incorporation into a variety of cosmetic formulations. Typical application directions include:
- Facial serums for daily skincare routines- Lightweight emulsions and lotions- Eye contour creams and gels- Leave-on masks and overnight treatments- Sheet masks and hydrogel patches- Pre-makeup primers and base products
1. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
2. Implications of ligand-receptor binding kinetics on GLP-1R signalling
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