(Phe13,Tyr19)-MCH (human, mouse, rat)

(Phe13,Tyr19)-MCH (human, mouse, rat) is a modified melanin-concentrating hormone analog containing aromatic substitutions that influence folding and hydrophobic interactions. The modifications support targeted assessment of receptor-binding domains. Its properties allow detailed analysis of neuropeptide regulatory networks. Researchers often use it to explore ligand-specific signaling characteristics.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: M03008

CAS No:160201-86-5

Synonyms/Alias:160201-86-5;NCGC00167177-01;DA-69177;FP108629;(Phe13,Tyr19)-MCH (human, mouse, rat) trifluoroacetate salt;Melanin-concentratinghormone(human),13-L-phenylalanine-19-L-tyrosine-(9ci);(Phe13,Tyr19)-MCH (human, mouse, rat) trifluoroacetate salt H-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Phe-Arg-Pro-Cys-Trp-Gln-Tyr-OH trifluoroacetate salt (Disulfide bond);H-Asp-Phe-Asp-Met-Leu-Arg-Cys-Met-Leu-Gly-Arg-Val-Phe-Arg-Pro-Cys-Trp-Gln-Tyr-OH; H-DFDMLRCMLGRVFRPCWQY-OH;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C109H160N30O26S4
M.W/Mr.
2434.9
Sequence
One Letter Code:DFDMLRCMLGRVFRPCWQY
Three Letter Code:H-Asp-Phe-Asp-Met-Leu-Arg-Cys(1)-Met-Leu-Gly-Arg-Val-Phe-Arg-Pro-Cys(1)-Trp-Gln-Tyr-OH
InChI
InChI=1S/C109H160N30O26S4/c1-57(2)45-74-90(148)122-54-85(142)123-68(27-17-39-118-107(112)113)95(153)138-88(59(5)6)104(162)134-77(48-61-23-13-10-14-24-61)97(155)128-73(29-19-41-120-109(116)117)105(163)139-42-20-30-83(139)103(161)137-82(102(160)132-78(50-63-53-121-67-26-16-15-25-65(63)67)99(157)125-70(35-36-84(111)141)92(150)135-80(106(164)165)49-62-31-33-64(140)34-32-62)56-169-168-55-81(101(159)127-72(38-44-167-8)93(151)130-74)136-91(149)69(28-18-40-119-108(114)115)124-96(154)75(46-58(3)4)131-94(152)71(37-43-166-7)126-100(158)79(52-87(145)146)133-98(156)76(47-60-21-11-9-12-22-60)129-89(147)66(110)51-86(143)144/h9-16,21-26,31-34,53,57-59,66,68-83,88,121,140H,17-20,27-30,35-52,54-56,110H2,1-8H3,(H2,111,141)(H,122,148)(H,123,142)(H,124,154)(H,125,157)(H,126,158)(H,127,159)(H,128,155)(H,129,147)(H,130,151)(H,131,152)(H,132,160)(H,133,156)(H,134,162)(H,135,150)(H,136,149)(H,137,161)(H,138,153)(H,143,144)(H,145,146)(H,164,165)(H4,112,113,118)(H4,114,115,119)(H4,116,117,120)/t66-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,79-,80-,81-,82-,83-,88-/m0/s1
InChI Key
RNCHKGYTHALNQH-SLTNFGAISA-N

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