Phthaloyl-L-Leucine

Name: Phthaloyl-L-Leucine
Brand: Creative Peptides
Rating: 5 (1 reviews)

Phthaloyl-L-Leucine is an N-phthaloyl protected derivative of the amino acid L-leucine, featuring a leucine side chain with an isobutyl group attached to the alpha carbon. The molecule contains a phthalimide-derived phthaloyl amide at the amino functionality, while the carboxyl group remains present as a free acid, and the stereochemistry corresponds to the L configuration indicated in the product name. In peptide chemistry and chemical biology, this protected amino acid is used as a building block to control chemoselectivity at the nitrogen during stepwise assembly of peptide or peptidomimetic structures, including workflows where an amide-protected amino group is required for selective coupling.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01313

CAS No:2419-38-7

Synonyms/Alias:PHT-LEU-OH;2419-38-7;Phthalyl-l-leucine;AC1LEMAT;N-Phthaloyl-L-Leucine;N,N-Phthaloyl-L-leucine;AC1Q1O9I;N-Alpha-phthaloyl-L-leucine;SCHEMBL4609039;ZINC57456;MolPort-001-794-424;RMOSZIHTPMEZAP-NSHDSACASA-N;AKOS023033847;AM20030430;(2R)-2-(1,3-dioxoisoindol-2-yl)-4-methylpentanoicacid;2-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)-4-methylpentanoicacid#

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M.F/Formula

C14H15NO4

M.W/Mr.

261.3

Abbr

Pht-Leu-OH

InChI

1S/C14H15NO4/c1-8(2)7-11(14(18)19)15-12(16)9-5-3-4-6-10(9)13(15)17/h3-6,8,11H,7H2,1-2H3,(H,18,19)/t11-/m0/s1

InChI Key

RMOSZIHTPMEZAP-NSHDSACASA-N

Canonical SMILES

CC(C)CC(C(=O)O)N1C(=O)C2=CC=CC=C2C1=O

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