Plasmepsin V FRET Substrate

Name: Plasmepsin V FRET Substrate
Brand: Creative Peptides
SKU: X21187
Availability: MadeToOrder

This FRET substrate peptide for Plasmepsin V (PMV) is derived from the conserved Plasmodium Export Element (PEXEL) motif of Histidine-Rich Protein II (HRPII). PMV is an ER aspartic protease that recognizes and cleaves the RXL sequence within the PEXEL motif of proteins exported by human malaria parasite Plasmodium falciparum, allowing them to translocate into host erythrocytes.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: X21187

Custom Peptide Synthesis

cGMP Peptide

Registration of APIs
CMC information required for an IND

IND and NDA support
Drug master files (DMF) filing

M.W/Mr.

1751.1

Sequence

One Letter Code: Dabcyl-LNKRLLHETQ-EDANS
Three Letter Code: Dabcyl-Leu-Asn-Lys-Arg-Leu-Leu-His-Glu-Thr-Gln-EDANS

References

Russo, I. et al. Nature 463, 632 (2010).

1. The spatiotemporal control of signalling and trafficking of the GLP-1R

2. Cationic cell-penetrating peptides are potent furin inhibitors

3. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes

4. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

5. Emu oil in combination with other active ingredients for treating skin imperfections

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